先天性肺囊腺瘤畸形的产前超声诊断与临床预后  

Prenatal Ultrasound Diagnosis and Clinical Prognosis of Congenital Cystic Adenomatoid Malformation of the Lung

作　　者：陈骊珠[1] 王晓光[1] 蔡爱露[1] 解丽梅[1] 王冰[1] 李婧宇[1] 

机构地区：[1]中国医科大学附属盛京医院超声科,沈阳市110004

出　　处：《中国超声医学杂志》2012年第3期221-224,共4页Chinese Journal of Ultrasound in Medicine

基　　金：国家十一五科技支撑计划项目(No.2006BA105A04);2010年辽宁省教育厅科研项目计划(No.L2010678)

摘　　要：目的探讨先天性肺囊腺瘤畸形(CCAM)的产前超声表现,评价疾病预后及发展过程。方法回顾性分析29例产前怀疑诊断先天性肺囊腺瘤胎儿的超声表现,并与产后结果进行对照分析。结果 29例孕妇中,19例选择中止妊娠,其中16例接受尸检,14例病理证实为CCAM,2例病理诊断为隔离肺合并CCAM;10例孕妇选择继续妊娠,其中1例胎儿出生后1个月因呼吸衰竭而死亡,余9例胎儿出生后至今均未出现呼吸系统症状。结论产前超声对CCAM的诊断是可靠的,在发现该病灶后,可应用超声观察病灶变化,单纯CCAM不合并胎儿水肿的患儿出生后预后较好。Objective To evaluate the sonographic apperances and prenatal natural history of congenital cystic adenomatoid malformation （CCAM） of the lung. Methods A retrospective study of 29 cases of prenatally detected CCAM was performed, and the diagnosis was contracted with the postnatal findings. Results A total of 29 cases were identified. The prengnaney was eleetively terminated in 19 cases, and 16 agreed autopsy, 14 were confirmed CCAM after autopsy, and the other two were confirmed pulmonary sequestration associated with CCAM. Among the remai- ning 10 pregnancies, 9 remained asymptomatic up to now, but 1 died of respiratory failure at one month. Conclusions The prenatal diagnosis of CCAM is reliable, and enable to predict the prognosis of the affected fetus. The fetus with isolated lung lesion without hydrops may have a good short-term prognosis.

关 键 词：超声 肺囊腺瘤 胎儿 

分 类 号：R445.1[医药卫生—影像医学与核医学] R734.2[医药卫生—诊断学]