氧气雾化联合化疗治疗初治痰菌阳性肺结核疗效分析  

Effective analysis on combined chemotherapy by oxyggen atomization administration in initially treating sputum positive pulmonary tuberculosis

作　　者：兰永会[1] 

机构地区：[1]泸县人民医院,四川泸县677200

出　　处：《现代医药卫生》2012年第6期820-821,共2页Journal of Modern Medicine & Health

摘　　要：目的探讨化疗联合氧气雾化和单纯化疗给药治疗初治痰菌阳性肺结核患者的疗效差异。方法将62例痰菌阳性肺结核患者随机分成两组各31例,实验组在常规抗结核治疗基础上给予异烟肼、阿米卡星联合沐舒坦氧气雾化吸入;对照组给予常规抗结核药物。结果疗程末,实验组和对照组痰菌阴转率分别为96.8%和77.0%,病灶吸收好转率分别为96.8%和74.1%,治疗2个月后症状缓解率分别为100.0%和64.5%。两组疗效对比差异有统计学意义(P<0.01)。结论在规范常规抗结核治疗的同时辅以氧气雾化治疗痰菌阳性肺结核疗效肯定,操作简单,患者易于接受,便于临床广泛应用。Objective To discuss the effects of pure chemotherapy and chemotherapy combined with oxygen atomization for initially treating sputum positive pulmonary tuberculosis（TB）.Methods 62 patients with sputum positive TB were randomly divided into two groups.On the basis of conventional anti-tuberculosis treatment,the experimental group（31 cases） was given isoniazid and amikacin combined with Mucosolvan oxygen inhalation.The control group（31 cases） was given the conventional anti-tuberculosis drugs.Results At the end of treatment,the sputum negative conversion rates in the experimental group and the control group were 96.8% and 77%,the focus absorption rates were 96.8% and 74.1%,the remission rates after two-month treatment were 100.0% and 64.5%,respectively.Comparing the curative effects between two groups showed statistical difference（P〈0.01）.Conclusion In standardization of systemic anti-tuberculosis treatment,at the same time assisted by oxygen atomization is definitely effective to treat sputum positive TB,which is simple to operate,easy to accept and convenient to widely carry out in clinic.

关 键 词：结核 肺 抗结核药 氧气雾化 痰菌阳性 

分 类 号：R521[医药卫生—内科学]