静脉滴注丙种球蛋白治疗新生儿ABO溶血疗效评价及护理  

Evaluation on effects of intravenous immune globulin in treating newborn ABO hemolysis and nursing care

作　　者：颜金花[1] 

机构地区：[1]四川省人民医院儿科,四川成都610072

出　　处：《现代医药卫生》2012年第5期747-748,共2页Journal of Modern Medicine & Health

摘　　要：目的评价静脉滴注丙种球蛋白(intravenous immune globulin,IVIG)在治疗新生儿ABO溶血中的疗效,为护理工作提供依据。方法将2010年1月至2011年10月在该院住院治疗的98例ABO溶血新生儿随机分为对照组和IVIG治疗组,比较两组间治疗前后的血清总胆红素水平及黄疸消退时间。结果治疗72 h后,IVIG治疗组血清总胆红素(105.11±46.56)μmol/L、黄疸消退时间(5.16±2.22)d,对照组为(142.23±47.47)μmol/L、(9.02±2.14)d,差异有统计学意义(P<0.05)。结论IVIG可有效阻断ABO溶血过程,迅速降低血清胆红素水平,缩短黄疸消退时间。护理ABO溶血患儿时应做好健康教育,密切观察病情变化,预防胆红素脑病的发生。Objective To evaluate the effects of intravenous immume globulin（IVIG） in treating ABO hemolytic disease to provide the basis for nursing work.Methods 98 cases of ABO hemolytic disease from January 2010 to October 2011 were divided into the IVIG group and the control group.Serum total bilirubin and jaundice fadeaway time before and after treatment were compared between the two groups.Results Serum total bilirubin in the IVIG group and the control group were（105.11±46.56）μmol/L and（142.23±47.47）μmol/L respectively;the jaundice fadeaway time in the IVIGl group and the control group were（5.16±2.22）d and（9.02±2.14）d respective,showing statistical difference between two groups（P0.05）.Conclusion IVIG may blockade the hemolytic process effectively,reduce the level of serum bilirubin and shorten the jaundice fadeaway time.In the nursing on the neonates with ABO hemolysis,the health education should be well conducted and the condition changes should be closely observed for preventing the happening of bilirubin encephalopathy.

关 键 词：ABO溶血 新生儿 黄疸 丙种球蛋白 静脉滴注 

分 类 号：R473.72[医药卫生—护理学]