正常成人大脑白质纤维磁共振弥散张量成像的定量研究  

Quantitative Analysis of Normal Adult Cerebral White Matter Fibers by Magnetic Resonance Diffusion Tensor Imaging

作　　者：武刚[1] 詹青霞[1] 丁小龙[2] 钟叶[1] 

机构地区：[1]复旦大学附属中山医院青浦分院放射科 [2]上海交通大学医学院附属第三人民医院放射科

出　　处：《中国医学计算机成像杂志》2012年第1期6-8,共3页Chinese Computed Medical Imaging

基　　金：上海市青浦区科委科研基金(N0.2009-34)~~

摘　　要：目的:运用弥散张量成像(DTI)定量研究正常成人脑白质不同解剖部位的各向异性特点。方法:对60名正常成人按年龄分成四组,均行DTI检查,分析其表面弥散系数(ADC)图及各向异性分数(FA)图的特点,并对不同解剖部位的脑白质进行ADC值及FA值的定量分析,通过统计学分析得出其弥散系数和各向异性特点。结果:不同年龄组间相同解剖部位脑白质ADC值及FA值的差异无统计学意义;不同解剖部位间FA值及ADC值的差异具有显著性。结论:DTI可清晰显示脑内白质的走行及方向,FA能准确定量分析正常成人不同部位脑白质纤维的各向异性程度。Purpose： To quantitative analyze the diffusion anisotropic features of normal adults cerebral white matter fibers by magnetic resonance diffusion tensor imaging. Methods： Sixty normal adults were divided into four groups according to their ages and were examined by magnetic resonance diffusion tensor imaging（DTI）. The apparent diffusion coefficient （ADC） maps and fractional anisotropy （FA） maps were analyzed. The ADC values and FA values were measured. And the statistical results were analyzed. Results： There was no significant difference between the ADC values and FA values of the same anatomical site of cerebral white matter in different age groups. There were statistical differences among FA values and ADC values of different anatomical parts. Conclusion： DTI could display the cerebral white matter fibers well. FA values can be used to analyze the anisotropy of different cerebral white matter fibers of normal adults quantitatively.

关 键 词：磁共振成像 弥散张量成像 白质纤维 成人 

分 类 号：R445.2[医药卫生—影像医学与核医学]