显微外科手术治疗脑动静脉畸形效果分析  

Analysis on efficacy of microsurgical exclusion in the treatment of arteriovenous malformation

作　　者：薛山[1] 张贤鹏[1] 

机构地区：[1]北京市仁和医院,北京102600

出　　处：《中国医药导报》2012年第8期68-69,71,共3页China Medical Herald

摘　　要：目的探讨显微外科手术治疗脑动静脉畸形(AVM)的临床效果。方法 61例脑动静脉畸形患者按照随机数字法平均分为显微外科手术组(31例)和血管内栓塞组(30例),分别接受显微外科手术治疗和血管内栓塞治疗。观察并比较两组术中出血量、术后GOS评分及术后并发症发生情况。结果显微外科手术组术中平均出血量[(362.4±70.8)mL]显著少于血管内栓塞组[(713.1±110.7)mL],差异有高度统计学意义(t=4.88,P<0.01)。术后GOS评分显示,显微外科手术组疗效较血管内栓塞组好,两组术后疗效优良率比较,差异有统计学意义(90.3%vs 63.3%,χ2=3.92,P<0.05)。两组均未发生明显并发症(6.5%vs 10.0%,χ2=1.33,P>0.05)。结论显微外科手术治疗脑动静脉畸形具有术中出血少、手术效果好、安全性高等优势,值得临床推广应用。Objective To explore the clinical efficacy of microsurgical exclusion in the treatment of arteriovenous malformation.Methods A total of 61 patients with arteriovenous malformation were randomly divided into microsurgical exclusion group（n = 31） and endovascular embolization group（n = 30）,all patients were received microsurgical exclusion or endovascular embolization.The amount of perioperative blood,postoperative Glasgow outcome scale（GOS） and complications were observed and compared.Results The mean amount of perioperative blood in microsurgical exclusion group [（362.4±70.8）mL] was significantly less than that in endovascular embolization group [（713.1±110.7）mL],there was a statistical difference between them（t =4.88,P 0.01）.Postoperative GOS score showed that the efficacy of microsurgical exclusion group was better than that of endovascular embolization group,there was an obvious difference in the good rate between microsurgical exclusion group（90.3%） and endovascular embolization group（63.3%）（χ2 =3.92,P 0.05）.No severe complication occurred between the two groups（6.5% vs 10.0%,χ2 =1.33,P 0.05）.Conclusion Microsurgical exclusion shows obvious advantages in less amount of perioperative blood,better efficacy and high safety in the treatment of arteriovenous malformation,thus it is worthy of applied in clinic.

关 键 词：脑动静脉畸形 显微外科手术切除 血管内栓塞 

分 类 号：R651.12[医药卫生—外科学]