金纳米颗粒等离子体共振吸收光谱检测头孢唑啉  

Detection of Cefazolin Based on the Plasmonic Resonance Absorption of Gold Nanoparticles

作　　者：李靖云[1] 王燚[1] 许佳丽[1] 李原芳[1] 

机构地区：[1]发光与实时分析教育部重点实验室,西南大学化学化工学院,重庆400715

出　　处：《应用化学》2012年第4期455-461,共7页Chinese Journal of Applied Chemistry

基　　金：国家自然科学基金(NSFC,20775061);西南大学大型仪器设备开放基金资助项目

摘　　要：根据金纳米粒子等离子体共振吸收引起的溶液颜色变化,建立了一种快速、简便检测头孢唑啉的色度分析方法。方法线性范围为0.1～5.0μmol/L,检测限为14 nmol/L。将该方法用于头孢唑啉钠粉针剂的分析,回收率在97.4%～100.2%之间,相对标准偏差小于6.1%。The cefazolin can be detected according to the change of solution color resulting from the plasmonic resonance absorption of AuNPs.The absorbance ratio at 520/660 nm of AuNPs is proportional to the concentration of cefazolin in the range of 0.1~5.0 μmol/L with the detection limit of 14 nmol/L.This method could be extended to the determination of cefazolin sodium powder injection,the recovery of cefazolin was in the range of 97.4%~100.2% while the relative standard deviation was less than 6.1%.

关 键 词：金纳米颗粒 头孢唑啉 氯化钠 等离子体共振吸收 色度法 

分 类 号：O657[理学—分析化学]