艾滋病住院患者137例死亡原因分析  

Analysis on the causes of death of 137 in-patients with acquired immune deficiency syndrome

作　　者：卢祥婵[1] 黄爱春[1] 欧汝志[1] 李雪琴[1] 邓建宁[1] 

机构地区：[1]南宁市第四人民医院感染科,广西530023

出　　处：《中国临床新医学》2012年第3期204-206,共3页CHINESE JOURNAL OF NEW CLINICAL MEDICINE

基　　金：广西"艾滋病和病毒性肝炎等重大传染病防治"科技重大专项课题(编号:2008ZX10001-008);广西卫生厅科研课题(编号:Z2010158);南宁市科学研究与技术开发及创新计划项目科研课题(编号:201003047C-1;201003047C-2)

摘　　要：目的探讨艾滋病(AIDS)住院患者的病死率及其死亡原因。方法对2010年住院期间死亡的艾滋病患者的临床资料进行回顾性分析。结果 2010年艾滋病住院患者共死亡137例,病死率为10.56%,其中男性105例,女性32例,比例为3.28:1,住院时间为(12.82±16.21)d,72.72%患者的CD4^+T细胞计数<100个/μl。接受高效抗逆转录病毒治疗(HAART)的患者HIV抗体确认阳性到死亡的时间明显长于未接受HAART治疗的患者(Z=-5.042,P=0.000)。最常见的导致患者死亡的原因为肺部感染、中枢神经系统感染、青霉病等。结论晚期AIDS患者病死率高,各种机会性感染仍是导致患者死亡的主要原因,HAART能明显延长艾滋病患者的存活时间。Objective To investigate the mortality rate and the causes of death of in-patients with acquired immune deficiency syndrome （AIDS）. Methods A retrospective study was done on the clinical data of AIDS pa- tients who died at the Fourth People＇ s Hospital of Nanning in 2010. Results There were 137 AIDS in-patients died in 2010 in the hospital and the mortality rate was 10. 56% , included 105 men and 32 female, the ratio of male to fe- male was 3.28： 1. The median length of hospital stay was （12. 82 ＋16. 21） days. 72. 72% patients were with CD4＋T cell count 〈 100/μl. The time from confirmation of HIV antibody positive to death in the patients accepted highly active anti-retroviral therapy（HAART） was significantly longer than that in the patients unaccepted HAART（Z = - 5.042, P = 0. 000）. The most common diseases caused death in these patients were pulmonary infection, infection of central nervous system and penicilliosis. Conclusion The mortality rate of the AIDS patients in advanced stage was high. Varieties of the opportunistic infections were also the main causes of the death in AIDS patients. And HAART may prolong the survival time of AIDS patients.

关 键 词：艾滋病 死亡原因 机会性感染 

分 类 号：R512[医药卫生—内科学]