异丙酚、瑞芬太尼抑制腹腔镜手术气腹反应临床探究  

Effect of propofol and remifentanil inhibit laparoscopic pneumoperitoneum reaction study

作　　者：包凤兰[1] 周艳[1] 

机构地区：[1]山东省济南市第一人民医院麻醉科,250011

出　　处：《中国医疗前沿》2012年第4期31-31,80,共2页China Healthcare Innovation

摘　　要：目的研究异丙酚与瑞芬太尼单独或联合应用对腹腔镜手术气腹应激反应的抑制效果。方法 160例ASAⅠ-Ⅱ级行腹腔镜手术的患者,随机分为异丙酚(A)组、瑞芬太尼(B)组、异丙酚-瑞芬太尼(C)组、对照(D)组。四组均以异丙酚、维库溴胺、瑞芬太尼诱导,并吸入异氟烷维持麻醉。比较各组气管插管后泵注药物前(T0),泵注药物后10min(T1)、气腹后5min(T2)、气腹后20min(T3)、停气腹前(T4)的SBP、HR、SNAP指数。结果异丙酚与瑞芬太尼单独或联合应用均可抑制腹腔镜气腹的应激反应。结论异丙酚与瑞芬太尼联合应用可更好的抑制腹腔镜气腹的应激反应。To study of propofol combined with remifentanil or separately on stress response to pneumoperitoneum in laparoscopic surgery of the inhibition effect. Methods 16o ASA I- Ⅱ level in patients with laparoscopic surgery, randomly divided into propofol（A） group, remifentanil（B） group, propofolremifentanil（C） group, control（d） group. Four groups to propofol, Vecuronium, and induced by remifentanil and inhalation anesthesia with isoflurane maintenance. Before the comparison group after endotracheal intubation： infusion drug（T0）, 10 minutes after drug infusion（T_1）, 5 minutes of pneumoperitoneum（T_2）, 20 minutes of pneumoperitoneum（T_3）, occlude anterior abdominal（T_4）, SBP, HR, SNAP index. Results Propofol and remifentanil or a combination can inhibit stress response of laparoscopic pneumoperitoneum. Conclusion Propofol and remifentanil combined with better inhibits stress response of laparoscopic pneumoperitoneum.

关 键 词：异丙酚 瑞芬太尼 腹腔镜 应激反应 

分 类 号：R614.2[医药卫生—麻醉学]