UNASYN的抗生素后效及临床研究  

THE POSTANTIBIOTIC EFFECT AND CLINICAL STUDY OF UNASYN

作　　者：吴尚为[1] 陈婕[1] 胡文芝[1] 王培福[1] 

机构地区：[1]天津医学院第二附属医院感染性疾病研究室,天津300210

出　　处：《中国抗生素杂志》1990年第4期296-302,共7页Chinese Journal of Antibiotics

摘　　要：本文对 Unasyn和氨苄青霉素进行了体外抗菌活性和抗生素后效应的比较研究。证实Unasyn对产β-内酰胺酶菌株的抗菌活性明显优于氨苄青霉素,其抗生素后效应也比后者长。同时在临床治疗的五例感染中,痊愈及显效的3例,好转1例,仅1例没有获得显著疗效。The antibacterial activities and postantibiotic effect (PAE) of Unasyn and Ampicillin in vitro were studied. The results showed that the antibacterial activities of Unasyn against β-lactamase postive strains were stronger than that of Ampicillin, and also Unasyn had longer PAE than Ampicillin did. In this study, We treated 5 patients with different infections by Unasyn. Among them, 3 patients were cured or got marked effect,1 patient was improved,and the other was no improvement.

关 键 词：UNASYN 抗生素后效应 临床研究 

分 类 号：R969.4[医药卫生—药理学]