长春西汀治疗后循环缺血性眩晕临床分析  

Clinical Study of Vinpocetine in Treatment of Vertigo Caused by Posterior Circulation Ischemia

作　　者：冯亚忠[1] 陈娇[1] 

机构地区：[1]上海交通大学附属第九人民医院奉城分院神经科,上海市201411

出　　处：《中华全科医学》2012年第4期527-528,共2页Chinese Journal of General Practice

摘　　要：目的观察分析长春西汀治疗后循环缺血性眩晕的疗效及优势。方法将110例患者随机分两组,其中治疗组60例,应用长春西汀30 mg加入5%葡萄糖液250 ml或生理盐水250 ml静点,1次/d,10 d为1个疗程。对照组50例,应用丹参20 ml加入5%葡萄糖液250 ml或生理盐水250 ml静点,1次/d,10 d为1个疗程。观察患者治疗前后临床表现和辅检指标(血、尿常规,血流变、血糖、血脂、肝肾功能、TCD、头部CT)。结果治疗组总有效率为95.00%,优于对照组的84.00%,治疗组不良反应轻微。两组2 d内起效率比较,P<0.05(治疗组88.33%,对照组52.00%),显示长春西汀治疗后循环缺血性眩晕起效快,疗效好,副作用轻微。结论长春西汀是一种良好的微循环改善剂,治疗后循环缺血性眩晕安全有效,起效快。Objective The observed and analyze the efficacy and advantages of vinpocetine in treatment of posterior circula tion ischemia. Methods One hundred and ten patients were randomly divided into two groups. The treatment group （60 cases） received vinpocetine 30 mg,intravenous drip,while the control group（50 cases） received salvia 20 ml,once a day, 10 days for a course of treatment in both groups. The clinical situation and some index （ blood and urine routine, hemorheology, blood sugar, blood lipids,liver and kidney function,TCD, brain CT） were observed before and after the treatment. Results The total effective rate was 95.00% in the treatment group,and was better than that of the control group with an effective rate of 84.00%. The ad verse reactions of treatment group were mild. The rate of taking effect on days 2 had a significant difference（ treatment group was 88.33 %, control group was 52.00%, P 〈 0.05 ）. Conclusion Vinpocetine is a good and safe agent which can improve microcir culation of patients, and is effective for the vertigo caused by posterior circulation ischemia.

关 键 词：长春西汀 后循环缺血 眩晕 

分 类 号：R543.5[医药卫生—心血管疾病] R441.2[医药卫生—内科学]