出国体检人员中可疑氯胺酮阳性病例确证分析  

Analysis of suspected case with ketamine positive among exit personel using drug affirming testing

作　　者：曹洁[1] 郑可芳[2] 黄金宝[1] 肖武[1] 张绍雨[1] 高博[1] 刘依德[1] 魏春华[1] 柯秋璇[1] 

机构地区：[1]福建国际旅行卫生保健中心国家毒品检测重点实验室,福建福州350001 [2]福建警察学院

出　　处：《中国国境卫生检疫杂志》2012年第1期21-26,共6页Chinese Journal of Frontier Health and Quarantine

基　　金：福建省青年基金项目(2011J05015)

摘　　要：目的建立一种快速、灵敏的方法用于氯胺酮初筛为阳性后的确证。方法采用传统的液-液萃取法进行人体尿液样品前处理,并结合单四极杆气相色谱质谱联用法(GC/MS)对样品进行确证分析。结果该氯胺酮初筛阳性尿样在确证分析中未检出氯胺酮。被检尿样的GC/MS谱图中未见明显的氯胺酮色谱峰;而经质谱定性后发现谱图中有较高的麻黄素色谱峰。结论本研究建立的GC/MS分析方法对于毒品确证十分准确、有效,可推广应用于其它毒品初筛为阳性的进一步确证实验中。Objective To establish a fast,sensitive affirming testing method to determine the result of ketamine in elementary drug testing.Methods Drug affirming testing was done using traditional liquid-liquid extraction as sample pretreatment and combining gas chromatograph-mass spectrometer（GC/MS） methods.Results The ketamine was not detected in drug affirming testing.There was no obvious ketamine peak in the chromatogram GC/MS methods.However the ephedrine peak can be observed distinctly in the chromatogram.Conclusion The new established GC/MS method is very exact and effective for ketamine affirming,so this method can be applied to other drug affirming testing.

关 键 词：氯胺酮 毒品 确证 单四极杆气相色谱质谱联用法 

分 类 号：R185[医药卫生—流行病学]