北京市MSM HIV、梅毒和HSV-Ⅱ感染及影响因素分析  

Prevalence and predictors of HIV,syphilis and herpes simplex type 2 virus(HSV-2) infections among the men who have sex with men(MSM)in Beijing

作　　者：高彦杰[1,2] 于明润[3] 李书明[2] 张政[2] 李东亮[2] 闫莉[4] 姜桂艳[4] 肖冬 罗凤基[2] 阮玉华[3] 邵一鸣 

机构地区：[1]河北医科大学公共卫生学院公共卫生学院流行病与卫生统计学教研室,河北石家庄050017 [2]北京市朝阳区疾病预防控制中心 [3]中国疾病预防控制中心 [4]北京京城皮肤病医院 [5]华人艾滋干预组

出　　处：《中国公共卫生》2012年第4期451-453,共3页Chinese Journal of Public Health

基　　金：国家科技部项目(2009ZX10004-903;2008ZX10001-016;2008ZX10001-004);美国国立卫生研究院(R01AI078933)

摘　　要：目的了解北京市男男性行为人群(MSM)的人类免疫缺陷病毒(HIV)、梅毒及单纯疱疹病毒Ⅱ型(HSV-2)的感染情况及影响因素。方法 2009年8-12月在北京市招募962名MSM进行一对一问卷调查,静脉取血进行HIV、梅毒和HSV-Ⅱ检测。结果在调查的962人中,最近6个月有91.27%(878/962)的人发生过肛交性行为,平均与3(范围1～413)名男性发生过性行为,有74.60%(655/878)在最近1次发生性行为时使用了安全套,49.66%(436/878)最近6个月在与男性肛交时每次都使用安全套;HIV感染率为6.34%(61/962),梅毒感染率为17.67%(170/962),其中活跃期梅毒感染率为9.88%(95/962),HSV-2特异性IgG抗体阳性率为5.30%(51/962);多因素Logistic回归分析显示:与HIV、活跃期梅毒、HSV-Ⅱ感染有统计学意义的因素分别是:非北京市户籍、近6个月与男性发生过性行为的人数>3人和活跃期梅毒;大专以下学历、HIV阳性和HSV-2阳性;年龄>25岁、大专以下学历、近6个月与男性发生过性行为的人数>3人、最近6个月与男性发生过无保护性行为、活跃期梅毒。结论北京市MSM人群HIV、梅毒及HSV-2感染率较高,应进一步加强有效的宣传教育和行为干预。Objective To study the prevalence and predictors of human immunodeficiency virus（HIV）,syphilis and herpes simplex type 2 virus（HSV-2） infections among MSM in Beijing.Methods The MSM were recruited with convenience sampling and investigated with a face-to-face questionnaire interview in Beijing ctiy between August to December,2009.Blood samples were collected to test HIV,syphilis,and HSV-2 infections.Results A total of 962 eligible MSM completed the inteview and blood sampling.The prevalence of HIV,syphilis,and HSV-2 infection was 6.34%（61/962）,9.88%（95/962）,and 5.30%（51/962）,respectively.Multivariate logistic regression analyses showed that HIV infection was associated with non-Beijing residence,having more than 3 sex partners in the latest 6 months,and recent syphilis infection.The syphilis imfection was associated with having the education level lower than college,with HIV infection,and posititve for HSV-2.The HSV-2 infection was associated with at age of more than 25 years,with lower education than college,having more than 3 sex partners in the latest 6 months,having unprotected sex in the past six month,and recent syphilis infection.Conclusion The MSM in Beijing had high infection rates of HIV,syphilis,and HSV-2 and effective education and behavior intervention should be conducted.

关 键 词：男男性行为者 活跃期梅毒 艾滋病 单纯疱疹病毒Ⅱ型(HSV-2) 感染率 

分 类 号：R377.1[医药卫生—病原生物学] R512.91[医药卫生—基础医学]