凤尾草化学成分研究  

Study on the Chemical Constituents of Pteris multifida

作　　者：舒积成[1] 潘景行[1] 张锐[1] 任晓静[1] 刘建群[1] 

机构地区：[1]江西中医学院现代中药制剂教育部重点实验室,南昌330004

出　　处：《中国药房》2012年第15期1383-1385,共3页China Pharmacy

基　　金：国家自然科学基金资助项目(30960495)

摘　　要：目的:研究凤尾草的化学成分。方法:应用硅胶、SephadexLH-20等柱色谱对凤尾草的化学成分进行分离、纯化,根据理化常数和光谱分析鉴定其结构。结果:从凤尾草中分离鉴定了8个化合物,分别为去咖啡酰基洋丁香苷(1)、肉丛蓉苷F(2)、洋丁香苷(3)、2β,14β,15α-trihydroxy-ent-kaur-16-ene(4)、2β,13β,14β,15α-tetrahydroxy-ent-kaur-16-ene(5)、7-羟基香豆素(6)、β-谷甾醇(7)、胡萝卜苷(8)。化合物1～6为首次从该植物中分离得到,化合物1、2、3、6为首次从该属中分离得到。结论:本试验结果可为凤尾草活性的进一步研究奠定基础。OBJECTIVE：To study the chemical constituents of Pteris multifida.METHODS：Compounds were isolated by silica gel and Sephadex LH-20 column chromatography and purified by recrystallization.Their structures were elucidated by spectral analysis and physicochemical properties.RESULTS：Eight compounds were isolated and identified as decaffeoylactecoside（1）,cistanoside F（2）,acteoside（3）,2β,14β,15α-trihydroxy-ent-kaur-16-ene（4）,2β,13β,14β,15α-tetrahydroxy-ent-kaur-16-ene（5）,7-hydroxy coumarin（6）,β-sitosterol（7）,daucosterol（8）.Compounds 1～6 were separated from the plant for the first time and compounds 1,2,3 and 6 were separated from the genus for the first time.CONCLUSION：The trial result lays a foundation for the activity study of P.multifida.

关 键 词：凤尾草 化学成分 分离 鉴定 

分 类 号：R284.1[医药卫生—中药学] R927[医药卫生—中医学]