复方地塞米松预防气管插管术后气道并发症的临床研究  

The clinical research of compound dexamethasone gel applied over tracheal tube to prevent postoperative airway complications

作　　者：郭海明[1] 庞志路[1] 孙政[1] 李佩涵[1] 韩雪萍[1] 

机构地区：[1]郑州大学第一附属医院麻醉科,河南郑州450052

出　　处：《河南医学研究》2012年第1期60-62,共3页Henan Medical Research

摘　　要：目的:探讨复方地塞米松软膏对全麻插管术后气道并发症的预防作用。方法:90例术前无任何呼吸道症状、无抽烟嗜好,ASA分级1～2级,拟在气管插管全麻下行单侧乳突根治术成人患者,随机分为3组,A组(复方地塞米松组,n=30)、B组(复方利多卡因乳膏组,n=30)和C组(石蜡油组,n=30),在插管前气管导管前端1/3分别均匀涂抹地塞米松软膏2 g、利多卡因软膏2 g和石蜡油,手术结束病人快速苏醒,术后随访评估气道并发症发生率和严重程度。结果:A组、B组与C组相比,术后气道症状的发生率明显降低(P<0.01),A组与B组相比,咳嗽的发生率较低(P<0.05),且C组的严重咳嗽、咳痰发生率高于A组和B组(P<0.01)。结论:复方地塞米松软膏能有效预防和降低术后气道并发症。Objective： To evaluate the effect of compound dexamethasone gel on the incidence and severity of airway symptoms induced by orotracheal intubation. Methods： Ninty adult patients without respiratory symptoms and smoking habits preoperatively were adopted.The patients had ASA classⅠ-Ⅱ levels and were treated with uni-lateral tympanoplasty under general anesthesia requiring orotracheal intubation.Patients were expected to quickly awake after the surgery.The patients were randomly divided into three groups including groupA,group B and the group C which were treated with compound dexamethasone gel,lidocaine gel and liquid paraffin respectively.The incidence and severity of postoperative respiratory symptoms were evaluated. Results： The incidence and severity of postoperative airway complications are lower in group A group B compared with group C（P〈0.05）;The incidence of cough in group A is lower than that of group B（P〈0.05）;the serious coughing and Much sputum cases of group C are more than group A and group B（P0.01）. Conclusion： Compound dexamethasone gel could effectively reduce the incidence of postoperative airway complications,and it can be promoted in the clinical practice.

关 键 词：术后咽喉痛 咳嗽 多痰 气管插管 

分 类 号：R619[医药卫生—外科学]