3.0T MR扩散加权和动态增强对乳腺小肿块性病灶的诊断价值  

Estimation of DWI and DCE-MRI in the small mass lesions of the breast on MR imaging at 3.0 T

作　　者：何之彦[1] Ateelesh Mangroo 李志宇[1] 姚戈虹[1] 李康安[1] 

机构地区：[1]上海交通大学医学院附属第一人民医院放射科,上海200080 [2]上海同济大学医学院附属同济医院放射科,上海200065

出　　处：《磁共振成像》2012年第2期120-124,共5页Chinese Journal of Magnetic Resonance Imaging

摘　　要：目的 3.0T MR扩散加权(DWI)和动态增强(DCE)对乳腺小肿块性病灶的诊断价值。方法回顾性分析62例采用MRI扩散加权和动态增强检查的乳腺良恶性病灶,其横轴像最大长径为10mm。结果常规的MRI的敏感性100%,特异性75.9%,与良性病变相比,恶性病灶的ADC值显著降低。利用受试者工作特性曲线(ROC)分析得出良恶性病变ADC值的分界值是1.11×10-3mm2/s。动力学曲线分析揭示II、III型曲线多考虑恶性。结论研究表明DWI和DCE-MRI技术易于评估。通过DWI获得的表观扩散系数(ADC)值能够用来鉴别良恶性乳腺肿瘤,从而使MRI具有较高的诊断敏感性和特异性。而且,动态增强后测得的动力学曲线对乳腺良恶性肿瘤的鉴别亦提供了较准确的判断。Objective： To assess the DWI and DCE-MRI in small mass lesions of the breast on MR imaging at 3.0 T. Materials and Methods： A retrospective study was conducted on 62 patients who underwent DWI and DCE-MRI as part of the clinical breast MRI protocol. Patients included in the study had breast lesions with a maximum length of 10mm as the long axis of the lesion on MR imaging. Results： The combined MRI protocol thus exhibited a sensitivity of 100% and a specificity of 75.9%. The ADC values were significantly lower in malignant lesions compared to their benign counterparts. ROC analysis revealed that the threshold value for ADC to distinguish between benign and malignant lesions is 1.11×10-3 mm2/s. Kinetic curve analyses revealed that type II and type III curves should be considered indicative of malignancy. Conclusions： The study demonstrates that DWI and DCE-MRI protocol is easy to carry out and assess. ADC values obtained from DWI can be used to distinguish between benign and malignant breast tumours. This MRI protocol has good sensitivity and specificity. Moreover kinetic curves obtained by DCE-MRI, provide a fairly accurate differentiation between benign and malignant tumours

关 键 词：磁共振成像 扩散加权成像 表观扩散系数:动态增强 乳腺病灶 

分 类 号：R445.2[医药卫生—影像医学与核医学] R737.9[医药卫生—诊断学]