磁共振扩散张量成像对脊髓型颈椎病的初步研究  

Preliminary study of diffusion tensor imaging in cervical spondylotic myelopathy

作　　者：宋春瑶[1] 王晓明[1] 

机构地区：[1]中国医科大学附属盛京医院放射科,辽宁沈阳110004

出　　处：《磁共振成像》2012年第1期19-23,共5页Chinese Journal of Magnetic Resonance Imaging

基　　金：盛京自由研究者基金项目资助(200802)

摘　　要：目的探讨扩散张量成像对检出脊髓型颈椎病颈髓早期损伤的敏感性。方法对13例健康志愿者和13例脊髓型颈椎病患者行常规MRI及扩散张量成像检查。测量C3～C7四组椎间盘层面的FA值、ADC值,并对所有受检者行颈髓纤维束重建。结果病例组ADC值大于对照组(t=8.495,P<0.001);病例组FA值小于对照组(t=-14.328,P<0.001),两者皆有统计学意义。病例组中约92.3%(12/13)患者脊髓受压部位伪彩图信号改变;约30.8%(4/13)患者T2WI脊髓内可见高信号,扩散张量成像比常规MRI对脊髓损伤更加敏感(P=0.002)。结论扩散张量成像可以提供脊髓的病理变化信息,在早期检出脊髓损伤方面比常规MRI敏感。Objective： To explore the sensibility of diffusion tensor imaging （DTI） in early detecting spinal cord injury in cervical spondylotic myelopathy. Materials and Methods： Cervical routine MRI and DTI were perlbrmed in 13 healthy volunteers and 13 patients with cervical spondylotic myelopathy. The radiological findings were analyzed, and the apparent diffusion coefficient （ADC） values and the fractional anisotropy （FA） values were calculated, and spinal cord fiber bundle was reconstructed. Results： Compared with control group, the mean ADC and FA values were higher （t=8.495, P〈0.00I） and the mean FA was lower （^-14.328, P〈0.001）, The DT1 color maps found abnormal signal at the compressed spinal cord. T2WI showed high signal at the compressed spinal cord in 4/13 （30.8%） patients. Fisher statistics proved that DTI was more sensitive than routine MRI （P=0.002）. Conclusion： DTI can provide information about the pathology. It is more sensitive in early detecting spinal cord injury in cervical spondylotic myelopathy than routine MRI.

关 键 词：磁共振成像 扩散张量成像 脊髓型颈椎病 

分 类 号：R445.2[医药卫生—影像医学与核医学] R681.55[医药卫生—诊断学]