牛骨胶原牛骨形成蛋白局部注射治疗骨折不连接12例  

Treatment of nonunions of long bones with bovine bone collagen-BMP by local injection in 12 cases

作　　者：丁真奇[1] 康两期[1] 翟文亮[1] 郭延杰[1] 练克俭[1] 郭林新[1] 

机构地区：[1]解放军第一七五医院骨科,漳州363000

出　　处：《中华创伤杂志》2000年第4期216-217,共2页Chinese Journal of Trauma

摘　　要：目的　观察牛骨胶原和牛骨形成蛋白 (BMP)复合后 ,局部注射于骨折端治疗骨不连的治疗效果。　方法　在X线机电视屏引导下 ,用小针刀在骨折端制造新鲜创伤后 ,局部注入 5～ 10ml牛骨胶原 牛BMP液。临床治疗 12例。　结果　 11例在 3～ 6个月获得临床骨折愈合 ,无并发症发生。　结论　牛骨胶原 牛BMP液骨折端局部注射治疗骨不连 ,是一种简单、有效且安全性高的方法。Objective To observe the clinical results of the composite of bovine bone collagen and bovine bone morphogenetic protein(BMP) for treatment of nonunions of long bones by local injection. Methods Fresh traumas in the site of fracture were again obtained by a small needle knife under the guide of X ray. Collagen/BMP (5-10 ml) was injected into the site of fracture of 12 patients. Results Except one patient, the clinical result and roentgenographic assessment were good in all. No complication happened. Conclusions The procedure is a simple, safe and effective method for orthopaedic patients.

关 键 词：胶原 骨折不愈合 骨形成蛋白 局部注射 

分 类 号：R683.05[医药卫生—骨科学]