楤木化学成分的研究  

Chemical constituents in Aralia chinensis

作　　者：洪良健[1] 窦芳[1] 田向荣[1] 王熠[1] 海文利[1] 汤海峰[1] 

机构地区：[1]第四军医大学西京医院药剂科,西安710032

出　　处：《中南药学》2012年第3期198-201,共4页Central South Pharmacy

基　　金：陕西省"13115"科技创新工程重大科技专项支助(编号:2010ZDKG-62)

摘　　要：目的研究楤木的化学成分。方法采用硅胶柱层析、Sephadex LH-20、ODS柱层析、半制备型高效液相色谱等分离方法进行分离纯化,经理化性质和波谱数据分析鉴定化合物结构。结果分离鉴定了4个三萜皂苷类化合物,分别鉴定为elatoside K methyl ester(Ⅰ)、araloside A methyl ester(Ⅱ)、pseudoginsenoside RT1butyl ester(Ⅲ)和太白楤木皂苷Ⅰ(Ⅳ)。结论化合物Ⅰ为新化合物,化合物Ⅱ～Ⅳ均为首次从该植物中分离得到。Objective To determine the chemical constituents from the roots of Aralia chinensis.Methods Column chromatography（including silica gel,Sephadex LH-20 and ODS）and semi-preparative HPLC were used to separate the chemical constituents.The structures were elucidated by analyzing the spectral data and chemical properties.Results Four triterpenoid saponins were isolated and elucidated as elatoside K methyl ester（Ⅰ）,araloside A methyl ester（Ⅱ）,pseudoginsenoside RT1 butyl ester（Ⅲ） and taibaienosideⅠ（Ⅳ）.Conclusion Compound Ⅰ is new and compound Ⅱ-Ⅳ have been separated from Aralia chinensis for the first time.

关 键 词：楤木 化学成分 三萜皂苷 

分 类 号：R284[医药卫生—中药学]