急性冠状动脉综合征患者血尿产生的影响因素分析  

Analysis of influencing factors on hematuria in patients with acute coronary syndrome

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作  者:徐鹏[1] 刘建云[1] 李勋[1] 

机构地区:[1]苏州大学附属第一医院心内科,215006

出  处:《中国医师进修杂志》2012年第10期4-6,共3页Chinese Journal of Postgraduates of Medicine

摘  要:目的探讨急性冠状动脉综合征(ACS)患者血糖、血压和血尿酸水平对血尿产生的影响。方法选择162例ACS患者,入院后即给予规范化治疗,行尿液分析并根据结果将患者分为无血尿组(37例,尿液离心沉淀后镜检红细胞〈3个,高倍镜视野)、镜下血尿组(56例,尿液离心沉淀后镜检红细胞≥3个,高倍镜视野)及肉眼血尿组(69例,每升尿液中含血量超过1m1)。测量各组血压、血糖、糖化血红蛋白、血尿酸,并进行比较。结果空腹及餐后2h血糖、糖化血红蛋白、收缩压及血尿酸水平镜下血尿组较无血尿组分别升高58.0%[(7.9±0.7)mmol/L比(5.0±1.1)mmol/L]、33.3%[(12.4±0.8)mmol/L比(913±0.6)mmol/LJ、48.2%[(8.3±0.8)%比(5.6±0.5)%]、23.8%[(151.6±7.0)mmHg(1mmHg=0.133kPa)比(122.5±9.9)mmHgj、29.2%l(635.4±47.4)μmol/L(491.8±83.4)μmol/L],差异有统计学意义(P〈0.05或〈0.01);肉眼血尿组上述指标较镜下血尿组分别升高16.5%[(9.2±1.1)mmol/L比(7.9±0.7)mmol/L]、30.6%[(16.2±1.8)mmol/L比(12.4±0.8)mmol/L]、14.5%[(9.5±0.8)%比(8.3±0.8)%]、18.8%[(180.1±12.3)mmHg比(151.6±7.0)mmHg]、34.6%[(855.5±74.5)μmol/Ltt(635.4±47.4)μmol/L],差异有统计学意义(P〈0.05或〈0.01);肉眼血尿组上述指标较无血尿组均显著升高(P〈0.01),但舒张压各组间比较差异无统计学意义(P〉0.05)。L06stic回归分析显示,除舒张压外,糖化血红蛋白(r=16.109,P=0.001)、空腹及餐后2h血糖(r=3.175,P=0.001;r=0.906,P=0.001)、收缩压(r=0.429,P:0.003)及血尿酸水平(r=1.317,P=0.004)均是ACS患者行抗栓治疗后产生血尿的危险因素,糖化血红蛋白和空腹血糖对产生血Objective To investigate the impact of blood glucose, blood pressure and blood uric acid level on hematuria in patients with acute coronary syndrome (ACS). Methods One hundred and sixty-two ACS patients were selected and received standardized treatment after admission to hospital. Urine test was taken and patients were divided into no hematuria group (37 cases), microscopic hematuria group (56 cases) and gross hematuria group (69 cases) according to the results. Blood pressure, fasting and postprandial 2 hours blood glucose, glycated hemoglobin and blood uric acid level were measured and compared among three groups. Results Microscopic hematuria group compared with no hematuria group, fasting and postprandial 2 hours blood glucose, glycated hemoglobin, systolic blood pressure and blood uric acid level raised 58.0% [ (7.9± 0.7) mmol/L vs. (5.0 ± 1.1 ) mmol/L ], 33.3% [ ( 12.4± 0.8) mmol/L vs.(9.3 ± 0.6) mmol/L] ,48.2%[ (8.3 ± 0.8)% vs.(5.6 ± 0.5)% ],23.8%[ ( 151.6 ±7.0) mm Hg ( 1 mm Hg = 0.133 kPa) vs. (122.5 ±9.9) mm Hg],29.2% [(635.4±47.4) p, mol/L vs. (491.8 ±83.4)μmol/L] respectively,there were significant differences (P 〈 0.05 or 〈 0.01 ). Gross hematuria group compared with microscopic hematuria group, the above mentioned indexes raised 16.5% [ (9.2 ± 1.1 ) mmol/L vs. (7.9 ±0.7 ) mmol/L], 30.6%[ ( 16.2 ± 1.8) mmol/L vs. ( 12.4 ± 0.8) mmol/L], 14.5%[ (9.5 ±0.8)% vs. (8.3 ± 0.8)% ], 18.8%[(180.1± 12.3) mm Hg vs.(151.6 ±7.0) mm Hg],34.6%[(855.5±74.5) μmol/L vs.(635.4 ± 47.4 )μ mol/L ] respectively, there were significant differenees (P 〈 0.05 or 〈 0.01 ). Gross hematuria group compared with no hematuria group, the above mentioned indexes increased significantly(P〈 0.01 ). The level of diastolic blood pressure among three groups had no signifieant differenee(P 〉 0.05 ). The Logistic regression analysis showed that fasting and postprandial 2 hours blood glucose (

关 键 词:血糖 血压 尿酸 血尿 

分 类 号:R541.4[医药卫生—心血管疾病]

 

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