巴曲抗栓酶治疗急性心肌梗死疗效观察  

Clinical effects of treating acute myocardial infarction with batroxobin

作　　者：宋丽绚 

机构地区：[1]兖州矿业(集团)有限集团公司第二医院内一科,山东邹城273500

出　　处：《临床心血管病杂志》2000年第5期221-222,共2页Journal of Clinical Cardiology

摘　　要：目的 :探讨巴曲抗栓酶治疗急性心肌梗死 (AMI)的临床疗效。方法 :30例 AMI患者在给予常规治疗的基础上 ,加用巴曲抗栓酶 ,分别于第 1、3、5天给予 1 0 u、5u、5u,以生理盐水 1 0 0 ml稀释后静脉滴注 1 h,与对照组比较 ,观察疗效及实验室指标。结果 :治疗 1周后 ,治疗组与对照组相比 ,左室射血分数增加 ,QT离散度减小 ,AMI后心绞痛发生率下降 ,纤维蛋白原明显降低 ,均有显著性差异。结论 :巴曲抗栓酶治疗 AMI具有改善左室功能 ,减少室性心律失常发生等作用 ,对发病延迟来院患者疗效好 ,使用方便、安全 ,值得推广。Objective:To explore the clinical effects of treating acute myocardial infarction(AMI).Method:30 cases of AMI patiens,beside routine treatment,were given batroxobin 10u,5u and 5u respectively on first,third and fifth day. Batroxobin was diluted in 100 ml of NS,then intravenously dripped for 1 hour to observe the effects and laboratory indexes and compared with the antithesis group(n=26).Result:After one week,comparing treatment group with the antithesis group,LVEF was increased and QTD was reduced,the occurring rate of angina pectoris was decreased,the fibrinogen(FIBEN) was reduced significantly.Conclusion:Batroxobin in treating AMI is able to improve the function of left ventricle and reduce the occurring of arrhythmias.It is of ideal clinical effects to treat AMI patients admitted to hospital lately.It is safe,convenient and worth recommending.

关 键 词：急性心肌梗塞 巴曲抗栓酶 药物疗法 

分 类 号：R542.220.5[医药卫生—心血管疾病]