经气管镜微创介入治疗146例支气管结核疗效分析  

Analysis on the clinical efficacy of the location interventional therapy under the bronchoscope in treating 146 cases bronchial tuberculosis

作　　者：魏喜玲[1] 梁占伟[1] 李志惠[1] 刘欣燕[1] 

机构地区：[1]河北省胸科医院内科,河北石家庄050041

出　　处：《临床肺科杂志》2012年第5期841-843,共3页Journal of Clinical Pulmonary Medicine

摘　　要：目的探讨经支气管镜综合介入治疗与单纯局部介入治疗支气管结核的临床疗效。方法将146例支气管结核病人随机分为5组,即单纯氩氦刀治疗组、高频电刀治疗组、冷冻治疗组、球囊扩张治疗组和综合治疗组(高频电刀或氩氦刀或冷冻治疗+球囊扩张),以上治疗均在全身标准四化抗结核治疗及辅助局部注药治疗的基础上进行局部微创介入治疗。观察比较经气管镜局部综合治疗组与各单纯局部治疗组的近期疗效。结果高频电刀组:平均治疗1.18次,有效率30.23%;氩气刀治疗组:平均治疗1.29次,有效率31.91%;冷冻治疗组:平均治疗0.55次,有效率15.00%;球囊扩张组:平均治疗0.73次,有效率18.69%;综合治疗组:平均治疗0.83次,有效率96.69%。结论支气管结核全身药物治疗疗效较差,辅助支气管镜局部综合介入治疗疗效显著,其疗效明显优于经支气管镜单纯介入治疗。Objective To explore the clinical effects of the general interventional therapy under the bronchoscope and singal location interventional therapy for bronchial tuberculosis.Methods 146 bronchial tuberculosis patients were randomly divided into 5 groups including singal argon helium knife（group A）,high frequency electrotome（group B）,cryotherapy（group C）,sacculus rotundus expanding（group D） and general therapy（group E）（group A or group B or group C＋group D）.Those five groups were treated by location interventional therapy based on standard anti-tuberculosis drugs treatment and local drug injection.The clinical efficacy of location general interventional therapy under the bronchoscope and singal location therapy was observed and compared.Results In the high frequency electrotome group,the average treatment frequency was 1.18 times and the total effective rate was 30.23%;In the singal argon helium knife group,the average treatment frequency was 1.29 times and the total effective rate was 31.91%;In the cryotherapy group,the average treatment frequency was 0.55 times and the total effective rate was 15.00%;In the sacculus rotundus expanding group,the average treatment frequency was 0.73 times and the total effective rate was 18.29%;and the general therapy average treatment frequency was 0.83 times and the total effective rate was 96.69%.Concluction The clinical efficacy of the standard anti-tuberculosis on bronchial tuberculosis was poor.However,the efficacy of the location interventional therapy under the bronchoscope were significant and more obvious than single interventional therapy under the bronchoscope.

关 键 词：支气管结核 支气管镜 介入治疗 疗效 

分 类 号：R521.2[医药卫生—内科学]