FeCl_3催化合成尼泊金丁酯及其酯化率测定方法  

A Study on FeCl_3 Catalized Synthesis of Butylparaben and the Determination of Its Esterification Rate

作　　者：竺宁[1] 林明丽[1] 洪海龙[1] 周利平[1] 闫丽岗[1] 

机构地区：[1]内蒙古工业大学化工学院,呼和浩特010051

出　　处：《内蒙古工业大学学报（自然科学版）》2012年第1期19-23,共5页Journal of Inner Mongolia University of Technology：Natural Science Edition

基　　金：内蒙古工业大学科学研究重点项目(ZD201106)

摘　　要：本文以对羟基苯甲酸和正丁醇为原料,在135-140℃下使用三氯化铁催化合成尼泊金丁酯,利用熔点、红外光谱与元素分析对目标产物的组成和结构进行表征。由于三氯化铁催化合成尼泊金丁酯时会影响现有酯化率的测定,本文使用K4[Fe(CN)6]消除三氯化铁对酯化率测定的影响,建立了精确测定酯化率的分析方法。Abstract： Butylparaben is synthesized through the reaction of 4 -hydroxybenzoic acid and n -butanol at135 - 140℃ with FeC13 · 6H20 used as the catalyst. The composition and structure of the target product are characterized by means of the melting point, IR and elemental analysis. However, the use of catalyst FeCl3· 6H：O would exert some adverse effect on the present analytic method for determining the esterification rate. Hence, by adding K4 [ Fe（ CN）6 to remove the effect of FeCl3, a new analytic method for accurate determina-tion of the esterification rate is devised.

关 键 词：三氯化铁 催化 尼泊金丁酯 酯化率 

分 类 号：TQ225.241[化学工程—有机化工]