胶东半岛地区金黄色葡萄球菌医院内感染检测分析  

Nosocomial infection surveillance of Staphylococcus aureus in Jiaodong Peninsula region

作　　者：董进浪 朱元祺[2] 苏维奇[3] 李笃军[4] 李延年[5] 吴金英[6] 林荣海[7] 

机构地区：[1]莱阳中心医院检验科,山东省莱阳市265000 [2]青岛大学医学院附属医院检验科,山东省青岛市266003 [3]青岛市市立医院检验科,山东省266011 [4]烟台经济技术开发区医院检验科,山东省烟台市264000 [5]青岛大学医学院附属西海岸医疗中心检验科,山东省青岛市266510 [6]烟台毓璜顶医院检验科,山东省烟台市264000 [7]威海市文登中心医院检验科,山东省文登市264400

出　　处：《中华实用诊断与治疗杂志》2012年第4期332-333,共2页Journal of Chinese Practical Diagnosis and Therapy

基　　金：山东省科技厅基金项目(2009GG0002057)

摘　　要：目的探讨胶东半岛地区金黄色葡萄球菌的临床感染特点及其耐药性。方法回顾性分析胶东半岛地区7家医院住院患者临床标本中分离的金黄色葡萄球菌的分布、标本来源及耐药情况。结果分离出金黄色葡萄球菌2 106株,其中耐甲氧西林金黄色葡萄球菌1 313株,占62.3%,主要来自神经内科、ICU、烧伤科、神经外科、皮肤科、呼吸科;痰标本和创面分泌物标本为耐甲氧西林金黄色葡萄球菌的主要标本来源,分别占63.7%和24.6%;金黄色葡萄球菌对临床常用抗生素的耐药率达60%以上,未发现对万古霉素耐药菌株。结论金黄色葡萄球菌在医院内分布广泛,多重耐药现象严重;及时了解耐甲氧西林金黄色葡萄球菌的分布特点及耐药状况,有助于控制医院内感染的发生和流行。Objective To study the clinical infection features and drug resistance of Staphylococcus aureus in Jiaodong Peninsula region.Methods The clinical distribution,source of sample and drug resistance of Staphylococcus aureus were analyzed retrospectively in the inpatients from 7 hospitals in Jiaodong Peninsula region.Results A total of 1 313 strains of methicillin-resistant Staphylococcus aureus accounted for 62.3% in all 2 106 strains of Staphylococcus aureus,mainly from departments of Neurology,ICU,Burn,Neurosurgery and Dermatology.The samples were mainly separated from sputum（63.7%） and wound（24.6%）.The resistance rate was over 60%,and vancomycin-resistant was not found.Conclusion Staphylococcus aureus is widely distributed in hospitals and multidrug resistance is severe.To get well informed of clinical infection features and drug resistance of methicillin-resistant Staphylococcus aureus helps to control the occurrence and prevalence of nosocomial infection.

关 键 词：金黄色葡萄球菌 耐甲氧西林金黄色葡萄球菌 耐药性 医院内感染 

分 类 号：R446.5[医药卫生—诊断学]