147株金黄色葡萄球菌耐药现状分析  

Drug-resistance analysis of 147 strains of Staphylococcus aureus

作　　者：韩飞[1] 李建英[1] 牟君成[1] 周政[1] 

机构地区：[1]重庆三峡中心医院微免科,404000

出　　处：《国际检验医学杂志》2012年第6期720-721,共2页International Journal of Laboratory Medicine

摘　　要：目的研究金黄色葡萄球菌(SAU)临床分离株的耐药性,为合理使用抗菌药物提供依据。方法采用VITEK2Compact型全自动微生物分析系统进行菌株鉴定和药敏试验,统计分析147株SAU的标本分布及耐药率。结果分泌物标本SAU检出率最高;耐甲氧西林金黄色葡萄球菌(MRSA)分离率达40.1%(59/147)。SAU对多种抗菌药物具有不同程度的耐药性,对呋喃妥因、利奈唑胺、奎努普汀/达福普汀、替加环素、万古霉素敏感率为100.0%。结论 SAU临床分离株耐药现状严重,MRSA的耐药情况更为严重,临床微生物实验室应加强MRSA监测工作。Objective To analyze the drug-resistance of Staphylococcus aureus（SAU） isolated from clinical samples,and provide scientific evidence for reasonable usage of antibiotics.Methods Clinical distribution and drug-resistance for 147 strains of SAU were analyzed by VITEK 2 Compact analyzer.Results Mainly of the 147 strains of SAU were isolated from secretion specimens.The isolating of methicillin resistant Staphylococcus aureus（MRSA） was 40.1 %（59/147）.Clinical isolates of SAU were resistant to antibiotics at different degree,with sensitivity rate of 100.0% to Nitrofurantoin,Linezolid,Quinupristin/Dalfopristin,Tigecycline and Vancomycin.Conclusion Drug-resistance status of SAU,especially MRSA,might be severe,and the monitoring of MRSA should be further strengthened in clinical microbiology laboratory.

关 键 词：金黄色葡萄球菌 耐甲氧西林金黄色葡萄球菌 耐药性 

分 类 号：R446.5[医药卫生—诊断学]