脐带间充质干细胞联合渗液吸收贴治疗Ⅱ、Ⅲ期压疮研究  

Umbilical cord mesenchymal stem cells partnering with exudate-absorbing dressings for the treatment of stage 2 or 3 pressure ulcers

作　　者：王运平[1] 刘玉芬[1] 闫秀杰[1] 严向芳[1] 孙悦[1] 陈然[1] 史晶[1] 

机构地区：[1]武警总医院神经干细胞移植科,北京100039

出　　处：《护理学杂志》2012年第7期55-56,共2页

摘　　要：目的探讨脐带间充质干细胞联合渗液吸收贴治疗Ⅱ、Ⅲ期压疮的临床效果。方法将36例脊髓损伤合并Ⅱ、Ⅲ期压疮患者随机分为对照组(Ⅱ期18处、Ⅲ期13处)和观察组(Ⅱ期24处、Ⅲ期压疮11处)。对照组采用常规治疗与护理方法;观察组采用脐带间充质干细胞联合渗液吸收贴治疗的方法,即局部清创、消毒后将1mL脐带间充质干细胞混悬液均匀涂抹于创面,并外敷渗液吸收贴。所有患者每2天换药1次,直至创面愈合。结果两组疗效比较,差异有统计学意义(P<0.05);两组显效时间和治愈时间比较,差异有统计学意义(均P<0.01)。结论脐带间充质干细胞联合渗液吸收贴可有效治疗Ⅱ、Ⅲ期压疮,并显著缩短创口治愈时间。Objective To investigate the effects of umbilical cord mesenchymal stem cells combined with exudate-absorbing dressings for the treatment of stage 2 or 3 pressure ulcers. Methods Thirty-six cases of spinal cord injury who suffered stage 2 or stage 3 pres- sure ulcers were randomly assigned to a control group （18 stage 2 and 13 stage 3 ulcers） and an observation group （24 stage 2 and 11 stage 3 ulcers）. The control group received conventional treatment and care, while patients in the observation group were subjec- ted to the treatment which combined umbilical cord mesenchymal stem cells with exudate-absorbing dressings： 1 mL of solution containing umbilical cord mesenchymal stem cells was applied to the pressure ulcer surface after local debridement and disinfection, and then the ulcer was covered with exudate-absorbing dressing. Dressing change was performed every day until healing of the ul- cer. Results Significant differences we：：e found in the total efficacy, the time from commence of the treatment to effect appearance, and the healing time between the two groups （P〈0.01 for all）. Conclusion Umbilical cord mesenchymal stem cells combined with exudate-absorbing dressings can be u,;ed to effectively treat stage 2 or 3 pressure ulcers and shorten the healing time.

关 键 词：脐带间充质干细胞 渗液吸收帖 压疮 

分 类 号：R472[医药卫生—护理学]