食管胃结合部腺癌临床病理特点  

Clinicopathological features of adenocarcinoma of the esophagogastric junction

作　　者：孙宇[1,2] 李吉友[1,2] 

机构地区：[1]北京大学肿瘤医院 [2]北京市肿瘤防治研究所病理科 恶性肿瘤发病机制及转化研究教育部重点实验室,北京100142

出　　处：《中国实用外科杂志》2012年第4期270-272,共3页Chinese Journal of Practical Surgery

基　　金：北京市科技新星计划项目(2009BG-02)

摘　　要：胃癌和食管癌是全球癌症相关死亡的主要原因之一。在发达国家,胃癌的发病率降低,与之相反,食管胃结合部腺癌(AEG)的发病率迅速上升。已有的文献表明AEG的病因、诊断标准及临床病理特征存在许多差异。许多AEG的组织发生与Barrett食管密切相关,发病经过从肠上皮化生→低级别异型增生→高级别异型增生→腺癌几个阶段。Gastric and esophageal cancers are among the leading causes of cancer-related death worldwidely. By contrast with the decreasing prevalence of gastric cancer, incidence and prevalence of adenocareinoma of the esophagogastric junction （AEG） are rising rapidly in developed countries. Many discrepancies exist in the published work about the causes, diagnostic criteria and clinicopathological features of AEG. Histogenesis of most AEG is related with Barrett＇ s esophagus. The pathogenic process includes intestinal metaplasia, low grade dysplasia, high grade dysplasia and adenocarcinoma.

关 键 词：食管胃结合部腺癌 诊断标准 临床病理特征 

分 类 号：R6[医药卫生—外科学]