原发性高血压肾病患者血清Hcy、vWF和D-D检测的临床意义  

Clinical Significance of Determination of Serum Hcy,vWF and D-D Levels in Patients with Essential Hypertension Nephropathy

作　　者：杨义伟[1] 

机构地区：[1]江苏省金坛市人民医院检验科,213200

出　　处：《放射免疫学杂志》2012年第2期205-207,共3页Journal of Radioimmanology

摘　　要：目的:探讨了原发性高血压肾病患者血清Hcy、血浆vWF和D-D水平的变化及临床意义。方法:应用免疫化学法和酶联法对38例原发性高血压肾病患者进行了血清Hcy、血浆vWF和D-D检测,并与35例正常健康人作比较。结果:原发性高血压肾病患者血清Hcy、血浆vWF和D-D水平非常显著地高于正常人组(P<0.01)且血清Hcy水平与血浆vWF、D-D水平呈正相关(r=0.2612、0.6823,P<0.01)。结论:原发性高血压肾病患者的发生发展与血清Hcy、血浆vWF和D-D水平密切相关。Objective To explore the clinical essential hypertension significance of changes on serun. Hey, vWF and D-D levels in patients with nephropathy. Methods Serun Hey（with immunoehemistry method） serun vWF, D-D （with ELISA）levels were meas- ured in 38 patients with essential hyper tension complicated with nephropathy as well as in 35 normal controls. Results Serun Hey, vWF and D-D levels were significantly higher than those in eentrols （ P 〈 0.01 ）. Serum Hey levels were significantly positively eerrelat- ed with the vWF, D-D levels （ r = 0.5612, 0. 6823, P 〈 0.01 ）. Conclusion Serun Hey, vWF and D-D levels increased distinctly in patients with essential hypertensin complicated with nephropathy and were mutually postively correlated.

关 键 词：原发性高血压肾病 同型半胱氨酸 血管性血友病因子 D-二聚体 

分 类 号：R544.1[医药卫生—心血管疾病]