盐酸米诺环素软膏辅助治疗种植体周围炎12例  

Local Administration of Minocycline Hydrochloride in the Adjuvant Treatment of Periimpalntitis

作　　者：周鑫才[1] 刘得玺[1] 石琦[1] 曹颖光[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院口腔种植中心,武汉430030

出　　处：《医药导报》2012年第4期438-440,共3页Herald of Medicine

摘　　要：目的评估盐酸米诺环素软膏治疗种植体周围炎的效果。方法 12例种植体周围炎患者(12枚种植体),彻底洁治,0.2%氯己定(洗必泰)冲洗,盐酸米诺环素软膏置入种植体周围袋袋底,分别在基线和治疗后4周测菌斑指数、龈沟出血指数和探诊深度,进行统计学分析。结果菌斑指数、龈沟出血指数和探诊深度分别由治疗前(2.42±0.79)分,(3.08±0.67)分,(5.44±0.64)mm,治疗4周后显著下降至(0.91±0.67)分,(1.33±0.88)分,(3.98±0.78)mm,差异均有统计学意义(P<0.05)。结论盐酸米诺环素软膏对种植体周围炎有较好辅助治疗作用。Objective To assess the clinical outcomes of peri-implantitis treated with local administration of minocycline hydrochloride.Methods Twelve patients with one implant each and being diagnosed as peri-implantitis were locally treated with minocycline hydrochloride after debridement and rinsing with 0.2% chlorhexidine solution.Plaque index,sulcus bleeding index,and probing depth were recorded at baseline and 4 weeks after the treatment,respectively.Results Plaque index,sulcus bleeding index,and probing depth were（2.42±0.79）,（3.08±0.67）,and（5.44±0.64） mm at baseline,and were（0.91±0.67）,（1.33±0.88）,and（3.98±0.78） mm at the forth week after the treatment,respectively.All differences were statistically significant（P0.05）.Conclusion The local administration of minocycline hydrochloride can be applied to treat peri-implantitis effectively.

关 键 词：米诺环素软膏 盐酸 氯己定 种植体周围炎 

分 类 号：R978[医药卫生—药品] R781.34[医药卫生—药学]