肺灌注SPECT/CT同机融合显像诊断肺栓塞的临床价值  

Clinical Diagnosis Value of Pulmonary Embolism by Pulmonary Perfusion SPECT/CT Co-registration Fusion Scintigraphy

作　　者：朱雁冬[1] 李广宙[1] 刘志祥[1] 于霞[1] 张磊[1] 谢海[1] 

机构地区：[1]潍坊医学院附属医院核医学科,山东潍坊261053

出　　处：《潍坊医学院学报》2012年第1期29-31,共3页Acta Academiae Medicinae Weifang

摘　　要：目的 评价肺灌注SPECT/CT同机融合显像对临床无创诊断肺栓塞（PE）的价值.方法 临床疑诊PE患者84例,男50例、女34例,年龄25～83岁,平均63.5岁.此84例患者均行99mTc.MAA肺灌注平面显像、SPECT断层显像和SPECT/CT同机融合显像,图像进行迭代重建.结果 本组84例患者中最终52例确诊为PE,肺灌注平面显像、SPECT断层显像和SPECT/CT同机融合显像诊断PE的灵敏度分别为63.5%,80.8%,94.2%,特异性分别为62.5%,84.4%和93.8%,准确性分别为63.1%,82.1%,94.0%,与文献报道肺通气/灌注（V/Q）显像诊断PE的准确性相近（85%～92%）.SPECT断层图像在诊断PE的灵敏度、特异性、准确性与平面图像比较差异明显（P〈0.05）;SPECT/CT融合图像诊断PE的灵敏度及准确性与SPECT断层显像相比亦具有显著性差异（P〈0.05）.结论 肺灌注SPECT/CT同机融合显像对临床无创诊断肺栓塞有重要意义.Objective To evaluate the clinical diagnosis value of pulmonary embolism hy pulmonary pertusion SPECT/CT co. registration fusion scintigraphy. Methods A total of 84 clinical patients who were st,spected of having PE,male50,female 34,25 83 years ohl, the average age was 63.5 years old. All 84 studies were underwent 99mTc. MAA puhnonary perfusion seintigraphy,including planar scintigraphy ,SPECT tomngraphy and SPECT/CT co. Registration fusion scintigraphy,the acquisition images were automatic processed and reconstun＇ted. Results Among 84 studies,52 were diagnosed pulmonary embolism final. The se.nsitivity of pulmona peffusion planar scintigraphy,SPECT tomography and SPECT/CT co. registration fusion scintigraphy was 63.5% ,80.8% and 94.2% respectively ;specificity was 62. 5% ,84.4% and 93.8% nspectively ; accuraev was 63. 1% , 82. 1 c, and 94.0% respectively. The accuracy （ 94.0% ） of SPECT/CT co. Registration fusion scintigraphy was similar to that of VentilatiotPerfusinn（ V/Q} seintigraphy reported in literatures（85qc 92% ）. Com- pared wilh planar image SPECT tomography image has significant difference in PE diagnosisgensitivity,specificity and accuracy（ P 〈0.05） ; Compared with SPECF tomography image SPECT/CT co. registration fusion image has significant differenee in sensitivity and accm＇acv either （P〈O. 05）. Conclusion Pulmona perfusion SPECT/CT co. registratinn fusion scintigraphy has imporiant clinical significance fnr PEg non. invasive diagnosis.

关 键 词：肺栓塞 肺灌注 SPECT/CT同机融合显像 肺通气/灌注显像 

分 类 号：R563.5[医药卫生—呼吸系统]