CdSe量子点标记免疫球蛋白及光谱性质研究  

Spectrum properties of immunoglobulin labelled with CdSe quantum dots

作　　者：刘晶莹[1] 王绍宁[1] 张莹[1] 

机构地区：[1]沈阳药科大学制药工程学院,辽宁沈阳110016

出　　处：《化学试剂》2012年第4期309-311,共3页Chemical Reagents

基　　金：沈阳大型科学仪器设备共享服务专项资助项目(2007GX-25)

摘　　要：以巯基乙酸为稳定剂合成了CdSe量子点,利用X-射线粉末衍射(XRD)和透射电镜(TEM)对量子点结构进行了表征,粒径约为5 nm。以碳二亚胺为缩合剂将量子点与免疫球蛋白共价连接,光谱实验结果表明CdSe量子点与免疫球蛋白有效结合,其荧光发射峰发生了红移,而半峰宽和发射强度没有明显变化。CdSe quantum dots （QDs） were synthesized by using thioglycollic scid as modifier. CdSe QDs were character- ized by X-ray powder diffraction （XRD） and transmission electron microscope （TEM）. The average size of QDs is about 5 nm. Immunoglobulin was labelled with CdSe QDs using car- bodiimide as condensating agent. The result showed immuno- globulin combined with CdSe QDs effectively. The maximum fluorescence emission shifted to red but the peak intensity and the peak width at half-height were not changed evidently.

关 键 词：CDSE量子点 标记 免疫球蛋白 光谱性质 

分 类 号：O614[理学—无机化学]