阿魏酸异辛酯的合成  

Synthesis of isooctyl ferulate

作　　者：肖鹏[1] 但飞君[1] 王银[1] 

机构地区：[1]三峡大学天然产物研究与利用湖北省重点实验室,湖北宜昌443002

出　　处：《化学试剂》2012年第4期369-371,共3页Chemical Reagents

摘　　要：丙二酸二乙酯部分水解、酸化后与香兰素进行Knoevenagel缩合得到中间体阿魏酸乙酯;之后与异辛醇发生酯交换合成标题化合物,总收率90.75%。本方法条件温和、操作简单、周期短,显著提高原子经济性,适合工业化生产。lsooctyl ferulate was synthesized from diethyl real- onate by hydrolysis, acidification, and then Knoevenagel con- densation reaction with vanillin to give ethyl ferulate, which was subjected to transesterification reaction with isooctanol with an overall yield of about 90%. This method was mild, simple,highly efficient, and atom-economic, which was suit- able for industrial production.

关 键 词：阿魏酸异辛酯 阿魏酸乙酯 KNOEVENAGEL缩合 酯交换 

分 类 号：O643.36[理学—物理化学]