儿童体位性心动过速综合征的发病机制  

Pathogenesis of Postural Orthostatic Tachycardia Syndrome in Children

作　　者：赵娟[1] 杜军保[1] 金红芳[1] 

机构地区：[1]北京大学第一医院儿科,北京100034

出　　处：《实用儿科临床杂志》2012年第7期540-542,共3页Journal of Applied Clinical Pediatrics

基　　金：国家"十二.五"支撑计划(2012BA103B03);北京市科技计划首都特色项目(D10100050010059)

摘　　要：体位性心动过速综合征是一种与体位有明确关系的窦性心动过速,特征性临床表现为当患者体位由平卧位转为直立时,于10 min内心率增加≥30次.min-1,或心率最大值≥120次.min-1。体位性心动过速的发病机制目前尚未明了,可能主要与中心血容量改变、自主神经及肌肉泵功能障碍、血管内皮功能异常以及基因变异等有关。Postural orthostatic tachycardia syndrome is a kind of nodal tachycardia which is definitely related to postural. It is defined as a sustained heart rate increase of≥ 30 times ·min^-1 or increase of heart rate to ≥ 120 times ·min^-1 within the first 10 min standing. Postural orthostatic tachyeardia syndrome is a clinical manifestation of multiple underlying mechanisms, such as the changes of central blood volume, dysautonomia, muscle pump dysfunction, endothelium function disorder of blood vessel, gene variation et al.

关 键 词：体位性心动过速综合征 发病机制 儿童 

分 类 号：R725.4[医药卫生—儿科]