双黄连粉针质控研究的概述与展望  

Quality Control of Shuanghuanglian Powder Injection

作　　者：高岚[1] 冯宇飞[1] 董立财[1] 吕邵娃[1] 王艳宏[1] 李永吉[1] 

机构地区：[1]黑龙江中医药大学,黑龙江哈尔滨150040

出　　处：《中医药信息》2012年第2期121-122,F0003,共3页Information on Traditional Chinese Medicine

摘　　要：分析了近年来研究双黄连粉针的文献并归纳总结。至目前为止,已发现的化学成分主要有黄酮类、有机酸、挥发油、萜类等;药理研究表明,双黄连粉针具有抗菌、抗病毒、消炎及调节免疫等作用;双黄连粉针质量控制方法多采用HPLC、TLC、HPCE及Fingerprint等方法。双黄连粉针作为中药注射剂的典型代表,限制其应用与发展的主要原因是缺乏统一有效的质控手段,建立高效的质控体系。促进化学与药敏实验相结合,将有利于双黄连粉针更好地服务临床。The paper reviews the medical journals on Shuanghuanglian powder injection in the recent years and summarizes them. Up to date, most of chemical compositions found are flavonoid, organic acid, essential oil, terpenoid and etc. The pharmacal researches show that it can antagonize bacteria and viruses, and can be anti- catarrhal, adjust immune function and so on. The methods of determination are HPLC, TLCS, HPCE, Finger- print and etc. As a typical representative of TCM injections, lack of unified and effective quality control meas- ure is the main reason for limiting its application and development. Establish a high effective quality control system and promote the combination of chemical and drug susceptibility test, then it can be more conducive to serve clinical application.

关 键 词：双黄连粉针 化学成分 药理作用 药动学研究 质量控制 研究进展 

分 类 号：R286[医药卫生—中药学]