固肾健脾方对绝经后骨质疏松妇女血清抵抗素、内脂素的影响  

EFFECTS OF GUSHEN JIANPI PRESCRIPTION ON SERUM RESISTIN AND VISFATIN OF POSTMENOPAUSAL OSTEOPOROSIS WOMEN

作　　者：陈树清[1] 杨玉彬[1] 孟君[1] 陈泽雄[1] 

机构地区：[1]中山大学附属第一医院,广州510080

出　　处：《中国中医药科技》2012年第2期107-108,95,共2页Chinese Journal of Traditional Medical Science and Technology

摘　　要：目的:探讨固肾健脾方对绝经后骨质疏松妇女血清抵抗素、内脂素的作用。方法:选择绝经后骨质疏松症患者85例,随机分为观察组43例,对照组42例。两组均给予钙尔奇口服,观察组再予固肾健脾方口服。采用酶联免疫吸附测定法分别在治疗前、治疗后3个月测定血清抵抗素、内脂素水平。结果:观察组治疗后内脂素水平均低于治疗前及同时间段的对照组,其差异有统计学意义(P<0.05);观察组治疗后抵抗素水平与治疗前及与同时间段对照组比较,其差异无统计学意义(P>0.05)。结论:固肾健脾方可以降低绝经后骨质疏松妇女内脂素水平,但对抵抗素的作用效果不明显。Objective: To explore the effects of gushen jianpi prescription on serum resistin and visfatin of postmenopausal osteoporosis women. Methods: 85 cases with postmenopausal osteoporosis were selected to be divided into observation group ( 43cases) and control group ( 42cases) ,both groups were given Gaierqi - D 600mg orally,observation group was given gushen jianpi prescription on the basis. Se- rum resistin and visfatin levels in the two groups were determined by ELISA method before treated and after treated for 3 months. Results: To compare with before treated,the visfatin level in observation group was obviously decreased after treated,and that was low- er than that in control group at the same time,the difference were significant; but the resistin level in the observation group had no ob- vious changes,there was no difference bttwecn before and after treated. Conclusion: Gushen jianpi prescription can reduce visfatin level of postmenopausal osteoporosis women. ,which has no significant effect on the resistin changes.

关 键 词：骨质疏松 绝经后/中医药疗法 @固肾健脾方/治疗应用 人类 

分 类 号：R285.5[医药卫生—中药学]