加味四妙勇安汤对冠心病患者血脂和血清高敏C反应蛋白的影响  

Effect of Modified Simiaoyong′an Decoction on Levels of Blood Lipids and Serum High-sensitivity C-reactive Protein in Patients with Coronary Heart Disease

作　　者：王道成[1,2] 冯霞 李七一[3] 

机构地区：[1]江苏省扬州市中医院,江苏扬州225009 [2]南京中医药大学,江苏南京210029 [3]江苏省中医院,江苏南京210029

出　　处：《中国中医急症》2012年第4期526-528,共3页Journal of Emergency in Traditional Chinese Medicine

基　　金：江苏省中医药局资助课题(NO.LZ11167)

摘　　要：目的研究加味四妙勇安汤对冠心病(CHD)患者血脂和高敏C反应蛋白(hs-CRP)的影响。方法将患者随机分为3组,均给予常规治疗,治疗组予加味四妙勇安汤口服,阿托伐他汀干预组予阿托伐他汀10mg晚餐后服,疗程均为6周。常规治疗组仅给予常规治疗。比较3组治疗前后血脂及血浆hs-CRP水平。结果 治疗组及阿托伐他汀干预组治疗后血清总胆固醇、三酰甘油、低密度脂蛋白胆固醇和hs-CRP水平下降程度均优于常规治疗组,组间疗效相近。结论加味四妙勇安汤对冠心病患者具有调脂和抗炎作用。To study the effect of Modified Simiaoyong＇an Decoction on the levels of blood lipids and the serum of high-sensitivity c-reactive protein（hs-CRP） in patients with coronary heart disease （CHD）. Meth- ods：Patients with CHD were divided randomly into 3 groups with routine therapies.The treatment group was given Simiaoyong^an Decoction and the intervention group was given atorvastatin. The treatment period was lasted for 6 weeks. Before and after treatment, fasting venous blood samples were collected to detect the concentration of blood lipids and hs-CRP. Results： After treatment, the serum total cholesterol （TC）, the triglyceride （TG）, the low density lipoprotein cholesterol （LDL-C） and the hs-CRP levels in treatment group and intervention group were all decreased significantly. These levels in above 2 groups were lower remarkably than those of in the con- ventional treatment group. Conclusion： Modified Simiaoyong＇an Decoction has lipid-regulating and anti-inflam- matory effects in CHD.

关 键 词：冠心病 血脂 高敏C反应蛋白 加味四妙勇安汤 

分 类 号：R541.4[医药卫生—心血管疾病]