氨转运蛋白Rh b型糖蛋白在大鼠肾脏皮质内髓 外髓的表达  

The expression of ammonia transporter Rhbg in cortex, outer medulla and inner medulla of kidney in rats

作　　者：刘伟[1] 罗静[2] 

机构地区：[1]太原市第三人民医院检验科,030012 [2]山西医科大学第二医院风湿科

出　　处：《中国药物与临床》2012年第4期441-444,共4页Chinese Remedies & Clinics

基　　金：山西省留学人员科研资助项目(2008102);山西省科学技术厅中美合作项目(2009081035)

摘　　要：目的观察氨转运蛋白Rhb型糖蛋白(Rhbg)在低蛋白饮食大鼠肾脏皮质、内髓和外髓的表达。方法利用蛋白印迹法分别检测低蛋白饮食组和正常对照组氨转运蛋白Rhbg在大鼠肾脏皮质、内髓、外髓的表达。结果低蛋白饮食可以明显增加Rhbg在大鼠肾脏皮质的表达(P<0.05),但不改变Rhbg在大鼠肾脏内髓和外髓的表达。结论饮食中蛋白的限制可能会增加Rhbg在大鼠肾脏皮质的表达。Objective To observe the expression of ammonia transporter Rhbg in cortex, outer medulla and inner medulla of kidney in rats. Methods Western blot was used to detect the expressions of ammonia transporter Rhbg in cortex, outer medulla and inner medulla in both group treated with low protein diet and normal control group, respectively. Results Low protein diet could significantly increase the expression of Rhbg in the cortex of rat kidney (P<0.05) but did not change that in outer medulla and inner medulla of rat kidney. Conclusion The limited protein diet may increase the Rhbg expression in the cortex of rat kidney.

关 键 词：肾皮质 肾髓质 载体蛋白质类 

分 类 号：R692[医药卫生—泌尿科学]