主动脉球囊反搏治疗心肌梗死后无复流和慢血流临床研究  

The Effect of IABP in No-Reflow and Slow-Flow After Primary PCI in AMI Patients

作　　者：范树信[1] 王旭[1] 邵一兵[1] 要英杰[1] 

机构地区：[1]青岛大学医学院,山东省青岛市266071

出　　处：《实用心脑肺血管病杂志》2012年第4期596-598,共3页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

摘　　要：目的研究主动脉球囊反搏术(IABP)对急性心肌梗死患者行PCI术后出现无复流/慢血流的治疗作用。方法将2006年—2011年在我院因心肌梗死行急症PCI出现无复流和慢血流的患者随机分为应用IABP和不用IABP的两组(慢血流和无复流患者分别分为应用IABP组和未应用IABP组),比较两组的患者BNP、醛固酮(ALD)、血管紧张素2(AngⅡ)、左室射血分数(LVEF)等的改善情况,从而评价IABP对PCI术后无复流/慢血流的治疗作用。结果应用IABP的患者BNP、ALD、AngⅡ较未应用IABP的患者峰值提前,降速增快,差异有统计学意义(P<0.05),应用IABP的患者EF值较未应用IABP的患者升高,差异有统计学意义(P<0.05)。结论应用IABP对改善心肌梗死行PCI后无复流/慢血流患者的预后起到积极作用。Objective To research the effect of intra - aortic balloon pumping （IABP） on no -reflow and slow - flow phenomenon in emergency pereutaneous coronary intervention （PCI）. Methods Clinical data of acute myocardial infarction pa- tients after PCI with angiographic no - reflow/slow - flow phenomenon were retrospectively analyzed between January 2006 anti December 2011. Patients were classified into IABP team and none - IABP team randomly. Observed differences of brain natri- uretic peptide, vasoaetive substances including aldosterone （ALD）, angiotensin I] （ANG Ⅱ ） in both groups on the clays of 1, 2, 3, 5, 7, 10 after the different interventions. In addition, left ventricular ejection fraction （LVEF） was evaluated after 10 days, 3 months, 6 months. Finally, statistics was token to analysis the data. Results The several, vasoactive substances as well as LVEF of 10 days, 3 months, 6 months of IABP groups had significant difference from control groups （ P 〈 0. 05 ）. BNP targets of IABP groups compared with the control groups had significant differences （P 〉 0. 05 ）. Conclusion IABP has effects on prognosis in AMI patients who performed PCI with angiographic no -reflow/slow -flow phenomenon.

关 键 词：心肌梗死 血管成形术 经腔 经皮冠状动脉 无复流现象 慢血流 主动脉球囊反搏 

分 类 号：R542.22[医药卫生—心血管疾病]