中药复方制剂抗猪流感病毒作用的研究  

Study on the Inhibiting Effects of Chinese Compound Recipe on Swine Influenza Virus

作　　者：张瑞华[1] 徐彤[1] 郑雪花[1] 李寸欣[1] 赵香汝[1] 薛拥志[1] 徐明举[1] 

机构地区：[1]河北北方学院动物科技学院,河北宣化075031

出　　处：《安徽农业科学》2012年第11期6534-6536,共3页Journal of Anhui Agricultural Sciences

基　　金：河北省教育厅项目(2011179);河北北方学院校内课题(Q201113)

摘　　要：[目的]探讨中药复方制剂(金银花、连翘、薄荷、牛蒡子、桔梗、甘草、淡竹叶、淡豆豉)对感染猪流感病毒小鼠的保护作用。[方法]猪流感病毒感染小鼠4 h后给药,以死亡率、平均存活时间、肺指数、肺指数抑制率、血凝滴度、脾脏指数、胸腺指数为评价指标,观察中药复方制剂在小鼠体内的抗流感病毒作用。[结果]中药复方制剂能降低流感病毒感染小鼠的死亡率(P<0.01),延长小鼠的存活时间(P<0.01),降低肺指数(P<0.01),降低血凝滴度(P<0.01),增加胸腺指数(P<0.01)。[结论]该中药复方制剂具有良好的抗猪流感病毒作用。[Objective] The aim was to discuss the antiviral activity of Chinese compound recipe（honeysuckle,forsythia,mint,burdock son,balloon flower,liquorice,light bamboo leaves,SSP） on mice infected with swine influenza virus.[Methods] Mice infected with swine influenza virus were treated with 4 h after infection,taking mortality,the mean survival time,lung index,lung index inhibitory rate,hemagglutination tite,spleen index and the thymus index as evaluation indexes,to observe the antiviral effect of Chinese compound recipe on anti-influenza virus in the body of mice.[Result] Chinese compound recipe can reduced the mortality of mice（P0.01）,prolonged the survival time of mice（P0.01）,reduced lung index（P0.01）,reduced hemagglutination tite（P0.01）,increased the thymus index（P0.01）.[Conclusion] Chinese compound recipe have good anti-influenza virus effect.

关 键 词：中药复方制剂 猪流感病毒 抗病毒 

分 类 号：S852.65[农业科学—基础兽医学] R451[农业科学—兽医学]