丙泊酚在重症哮喘机械通气患者中的镇静效果观察  被引量:2

The Sedative Function of Propofol in Severe Asthma Mechanical Ventilation

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作  者:王家珍[1] 吴天清[1] 蒋莉[1] 邹健金 

机构地区:[1]四川省三台县人民医院重症医学科,四川三台621100

出  处:《中国医药指南》2012年第9期333-334,共2页Guide of China Medicine

摘  要:目的探讨丙泊酚在重症哮喘机械通气中的镇静效果。方法采用有创机械通气治疗的重症哮喘患者36例,随机分为治疗组18例给予丙泊酚镇静,对照组18例给予咪唑安定镇静,二组均给予容量辅助/控制通气模式,根据病情调整呼吸机参数,其余治疗哮喘的方法相同。结果治疗组和对照组的治愈率分别为92.86%和90.15%无统计学差异。但气管插管时间治疗组为(2.4±0.33)d,对照组为(3.6±0.25)d,平均住ICU时间治疗组和对照组分别为(4.3±0.16)d,(5.5±0.18)d,呼吸机相关性肺炎(VAP)发生率分别为5.56%和11.11%均有明显的统计学差异。结论丙泊酚镇静在重症哮喘机械通气中具有起效快、苏醒迅速的特点,它可以减少带呼吸机时间,缩短住ICU时间,减少呼吸机相关性肺炎的发生率。Objective To investigate the sedative function of Propofol in severe asthma mechanical ventilation sufferer.Methods 36 severe asthma sufferers were randomly divided into Propofol treatment group and Midazolam control group.Two groups were treated in the same ventilalion mode assist/ controlled ventilation(A/C) for the rest theatment idem.Results The cure rate of Propofol treatment group(92.86%) and Midazolam control group(90.15%) were no statistical significant difference(P0.05).The time of intubation tube Propofol treatment group(2.4±0.33) and Midazolam control group(3.6± 0.25) were significantly statistical significant(P 0.05).The time stay in ICU and ventilator-associated pneumonia incidence were statistical significant difference(P 0.05).Conclusion Propofol perhaps could decrease the time of intubation tube and decurtate stay in intensive-care-unit,At the same time propofol could reduce ventilator-associated pneumonia incidence.

关 键 词:重症哮喘 机械通气 丙泊酚 镇静 

分 类 号:R562.25[医药卫生—呼吸系统]

 

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