气管内吹气在急性呼吸窘迫综合征患者中的应用  

Effects of tracheal gas insufflation in patients with acute respiratory distress syndrome

作　　者：杨彦楠[1] 陈秀云[1] 徐网兰[1] 皮白雉[1] 姚小英[1] 程新财[1] 

机构地区：[1]武警浙江总队医院重症监护室,浙江嘉兴314000

出　　处：《中国急救医学》2012年第4期346-348,共3页Chinese Journal of Critical Care Medicine

摘　　要：目的观察在小潮气量机械通气基础上应用气管内吹气（trachealgasinsuffiation，TGI）对实施允许性高碳酸血症（PHC）的急性呼吸窘迫综合征（ARDS）患者的疗效，并探讨其机制。方法对我院鼬年来诊断明确的ARDS患者在小潮气量机械通气、PHC基础上应用我院自行设计的气管内吹气装置持续TGI，低流量（2L／min）吹入新鲜气体治疗2h，每30min记录动脉血气（PaCO2、PaO2）、潮气量、血氧饱和度（SaO2）、吸气峰压（PIP）、平台压（Plat）、呼气末正压（PEEP）、心率和平均动脉压（MAP）。结果在各时间段气管内吹气后PaCO，较吹气前下降，120rain组差异有统计学意义。结论应用自行设计的气管内通气装置在ARDS患者中短期实施气管内吹气，可以改善PHC，降低呼吸机的支持条件。Objective To evaluate the effects of tracheal gas insufflation in adult with acute respiratory distress syndrome who were utilize low tidal volume and approach mechanism. Methods ARDS with permissive hypercapnia were assigned to TGI （continuous TGI flow at a rate 2 L/min was introduce ） for 2 hour. Values of arterial blood gas analysis, PIP, Plat, PEEP, Heart rate, mean arterial blood pressure were recorded every 30 min. Results TGI resulted decrease in PaCO2, respective as compared with baseline, furthermore 120 min group difference was statistical significance. Conclusion Homemade tracheal ventilation device to implement TGI can improve PHC, reducing support conditions of ventilator.

关 键 词：急性呼吸窘迫综合征(ARDS) 允许性高碳酸血症(PHC) 机械通气 解剖无效腔 气管内吹气(TGI) 

分 类 号：R563.8[医药卫生—呼吸系统]