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出 处:《中国实用医刊》2012年第9期41-44,共4页Chinese Journal of Practical Medicine
摘 要:目的评价海藻酸钠微球(KMC)作为栓塞材料在部分脾栓塞术(partialsplenicembolization,PSE)治疗肝癌肝硬化脾功能亢进年的疗效及并发症。方法156例脾亢行PSE患者,栓塞材料为KMC,平均栓塞范围65%以上,随访观察外周血白细胞、血小板和红细胞计数变化及术后反应。结果本研究所有患者随访1周、2周、1个月、6~9个月,脾功能亢进的症状均有不同程度缓解,同时有效改善了外周血象。结论KMC微球可作为PSE栓塞材料,栓塞程度控制在50%~70%可有效治疗脾亢,减轻术后反应。Objective To evaluate the efficacy and complications of partial splenic emboli- zation(PSE) with KMC for patients with liver cancer and hypersplenism. Methods One hundred and fifty-six patients with hypersplenism and cirrhosis were treated by PSE with KMC, the average embolism area was above 65 % of the spleen ; peripheral white blood cells counts (white blood cell, WBC), platelet (PLT) and red blood cell (RBC) and the complications of PSE were observed. Results Then the clinical reactions and results of patients were observed in all the cases from 1-2 weeks to 9 months follow-up, the hypersplenism symptoms of all patients were alleviated in different degrees. Meanwhile, the peripheral hemogram was effectively ameliorated. Conclusions KMC may be used as the embolic material of PSE with embolization degree ranging from 50% -70% , which may alleviate hypersplenism in patients with liver cancer, and also decrease the incidence of post - emboli- zation complications.
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