定功率变流量气冷射频消融方式效果研究  

Efficacy of Gas-cooled Radiofrequency Ablation Mode with Constant Power and Varying Flow Rate

作　　者：赵庆孝[1] 常兆华 杨鹏飞[3] 

机构地区：[1]上海理工大学,上海200093 [2]上海导向医疗系统有限公司,上海201318 [3]国家食品药品监督管理局医疗器械技术审评中心,北京100044

出　　处：《航天医学与医学工程》2012年第2期126-130,共5页Space Medicine & Medical Engineering

摘　　要：目的验证一种定功率变流量以维持T0.2(距射频针0.2 cm处的温度)于设定值的气冷射频消融方式的可行性及有效性。方法以土豆为实验对象,设计了针对不同T0.2预设值、氮气压力、射频功率的3组实验,通过考察射频针周围组织升温幅度及升温速度确定上述3个参数对消融效果的影响。结果T0.2预设值越高,周围组织升温幅度越大;如能维持T0.2于预设值,则升温效果与氮气压力无关;同样时间内,升温幅度随功率增大而增大,但超过一定功率值后,由于消融时间缩短,升温幅度反而逐渐减小。结论定功率变流量的气冷射频消融方式优于同工况下的传统气冷射频消融方式,实验结果可为气冷射频技术的优化提供参考。Objective To verify the feasibility and efficacy of a new radiofrequency ablation（RFA） mode with constant power and varying gas flow rate to keep T0.2（the temperature 0.2 cm away from the RF probe）at the presetting temperature.Methods Three groups of experiments were performed according to different presetting value of T0.2,gas pressure and RF power in potatoes.The effects of the former 3 parameters mentioned above on ablation efficacy were evaluated by the degree and the rate of temperature rise of the tissue around the probe.Results The higher the presetting value of T0.2,the larger the degree of temperature rise of tissues was;If T0.2 could be kept at the preset value,the temperature rise was not related to the nitrogen pressure;In the same ablation duration,the degree of temperature rise was in direct proportion to the power.But when the power reached a certain level,the former was in contrast with the latter because of the ablation duration getting shorter.Conclusion The new RFA mode is superior to the regular one.The results provide helpful references for the optimization of gas-cooled RFA technology.

关 键 词：气冷射频针 温度 升温 消融 

分 类 号：R318.52[医药卫生—生物医学工程]