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作 者:史彦章 李桂[2] 贾凤新 高向红[3] 云雅卿 王永辉
机构地区:[1]邱县中心医院内科,河北邱县057450 [2]石家庄平安医院风湿免疫科,河北石家庄050021 [3]邯郸市中医院内科,河北邯郸056000 [4]高阳县中医院内科,河北高阳071500
出 处:《中华中医药学刊》2012年第4期810-812,共3页Chinese Archives of Traditional Chinese Medicine
基 金:河北省中医药管理局中医药科学技术研究专项课题资助项目(2011012)
摘 要:目的:研究白塞氏综合征(BD)患者治疗前后负性情绪和生活质量的变化及清补活血法的干预作用,进一步评价清补活血法对BD的临床疗效。方法:将符合入选标准的108例BD患者,随机分为清补活血汤组(治疗组)54例,泼尼松组(对照组)54例。采用焦虑自评量表(SAS)、抑郁自评量表(SDS)、SF-36生存质量测定表进行问卷调查,采用半定量症状分级法对BD患者相关临床症状积分统计,进行前后对比治疗研究。结果:BD患者焦虑抑郁指数(SAS+SDS积分)较健康人明显升高(P<0.05);BD患者生活质量(生理功能、生理职能、躯体疼痛、总体健康、活力、社会功能、情感职能和精神健康)有不同程度的下降,与健康人比较有显著性差异(P<0.05或P<0.01);经治疗后两组患者上述各观察指标有不同的升落,与治疗前比较有显著性差异(P<0.05或P<0.01),治疗后治疗组与对照组比较,差异有显著性(P<0.05或P<0.01)。结论:BD患者处于轻中度精神抑郁状态,生活质量有一定程度的下降,清补活血法可改善BD患者的负性情绪,提高生活质量。Objective: The changes of negative emotions and life quality of BD patients before and after treatment were compared and the intervention of clear supplementing and blood-activating method was studied so as to evaluate the effect.Methods: 108 cases met the criterion were involved and randomly divided into treatment group(54 cases) and control group(54 cases).SAS,SDS and SF-36 surviving testing table were used.Clinical symptoms scores comparison was made by semiquantitative symptom grading method.Results: The anxiety-depression index(SAS+SDS) of BD patients obviously increased than that of healthy people(P0.05);quality life of BD patients had decreased in and compared with healthy people,there was significant differentce(P0.05 or P0.01).After treatment,the above indexes have different increase and decrease;and there was significant difference compared before treatment.The comparison before and after treatment had obvious differences(P0.05 or P0.01).Conclusion: BD patients are in moderate depression condition and the life quality has decreased to some extent.Clearing supplementing and blood-activating method can rectify the negative emotions and improve life quality.
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