更昔洛韦联合免疫球蛋白治疗小儿急性病毒性脑炎疗效观察  

Clinical Efficacy of Ganciclovir Combined with Immunoglobulin in Treatment of Children with Acute Viral Encephalitis

作　　者：罗利华[1] 

机构地区：[1]四川省巴中市巴州区妇幼保健院,四川巴中636001

出　　处：《中国医学创新》2012年第11期39-40,共2页Medical Innovation of China

摘　　要：目的:探讨更昔洛韦联合免疫球蛋白(IVIG)在治疗小儿急性病毒性脑炎(AVE)中的作用。方法:对82例小儿AVE患者,按入院先后顺序随机分为观察组和对照组,每组41例。对照组给予更昔洛韦治疗,而观察组给予更昔洛韦联合IVIG治疗,对两组的临床疗效指标进行观察。结果:观察组在疗效及病程方面明显优于对照组,未见明显不良反应,组间比较差异有统计学意义(P<0.05)。结论:更昔洛韦联合IVIG是治疗急性病毒性脑炎的一种安全有效的措施,优于单用更昔洛韦治疗,具有重要价值,值得临床推广。Objective：To explore the clinical efficacy of ganciclovir combined with immunoglobulin （IVIG） in treatment of children with acute viral encephalitis.Methods：According to the admission,82 children with acute viral encephalitis were randomly divided into observation and control group（n=41）.The control group was given ganciclovir treatment,while the experimental group given ganciclovir IVIG therapy. On two groups of clinical effectiveness indexes were observed.Results：Efficacy and duration of the observation group is better than the control group.the difference was significant between groups （P〈0.05）.The two groups showed no significant adverse effects.Conclusion：Ganciclovir combined with IVIG is a safe and effective measures to better than ganciclovir in treatment of children with acute viral encephalitis,have important clinical value and is worthy of promotion

关 键 词：免疫球蛋白 更昔洛韦 小儿 急性病毒性脑炎 

分 类 号：R725.1[医药卫生—儿科]