32例急性化脓性胆管炎细菌培养及药敏分析  

Bacterial culture of 32 patients with acute suppurative cholangitis

作　　者：薛鸿鹏[1] 祝喜萍[1] 刘晨[1] 李强[1] 林喜杰[1] 姜子晔[1] 朱春兰[1] 任旭[1] 

机构地区：[1]黑龙江省医院附属消化病医院,黑龙江哈尔滨150001

出　　处：《中国校医》2012年第4期286-286,288,共2页Chinese Journal of School Doctor

摘　　要：目的了解急性化脓性胆管炎细菌培养及药敏分析结果。方法对32例应用内镜治疗的急性化脓性胆管炎患者术中抽取胆汁进行细菌培养、药敏分析。结果 32例患者中,26例(81.25%)分离出致病菌株64株,其中革兰阴性杆菌34株,占53.12%,共检出革兰阳性球菌30株,占46.88%,大肠埃希菌对亚胺培南、头孢他定、头孢曲松的敏感率分别为93%、87%、82%;肺炎克雷伯菌对亚胺培南、阿米卡星、头孢曲松的敏感率为100%、85%、81%;肠杆菌药物的敏感性较差;铜绿假单胞菌虽然对亚胺培南、阿米卡星敏感性较高。革兰阳性球菌中主要为粪肠球菌,对万古霉素、亚胺培南的敏感率为93%、88%。葡萄球菌属仅对万古霉素敏感。结论实际工作应依据细菌培养及药敏结果调整抗生素的使用,避免滥用抗生素减少耐药菌株的出现。Objective To understand the status of bacterial culture and sensitivity of patients with acute suppurativecholangitis. Methods A total of 32 acute suppurative cholangitis patients who received endoscopic treatment underwent the bilecollection fol- bacterial culture and sensitivity analysis, Results Totally 64 strains of pathogenic bacteria were isolated from 26cases （81.25 % ） among the 32 patients, and the bacteria induded gram-negative bacilli （34, 53.12 % ） and Gram-positive oocei（30, 46.88% ）. The sensitivity rates of Escherichia bacteria to imipermaa, cdtazidime and ceftriaxone were 93%, 87 % and82% respively; the sensitivity rates of Klebsiella pneumoniae to imipenem, amikacin and ceftriaxone were 100%, 85% and 81% respectively; Enteabateriaceae was less sensitive to the drugs. Pseudamanas aeruginosa was higher sensitive to imipenem and amikacin. The sensitivity rates of Gram-positive cooci, mainly Enteroooocus faecalis, were 93% and 88% to vacomaycin andimipenern respectively. Staphytloooocus aureus was only saxsitive to vaneernycin. Comclosions In the practice, physicians shouldadjust the use of antibiotics based on bacterial culture and sensitivity re：suits, so as to avoid the abuse of antibiotics to reduce the of resistant strains.

关 键 词：胆管炎/病因学 细菌/分离与提纯 微生物敏感性试验 

分 类 号：R657.45[医药卫生—外科学]