肾移植后糖尿病  

Posttransplantation diabetes mellitus

作　　者：姚许平 胡勤勇 陈赐龄[2] 

机构地区：[1]浙江鄞县人民医院泌尿外科,315040 [2]苏州医学院附属第一医院泌尿外科

出　　处：《中华外科杂志》2000年第1期67-68,共2页Chinese Journal of Surgery

摘　　要：目的　研究肾移植后糖尿病 (PTDM)的临床规律。　方法　总结 1992年 12月至 1998年 9月间经治的 2 1例PTDM患者与同期非PTDM患者 10 8例的资料比较。　结果　本组PTDM总发病率为 16 3%。统计显示 ,PTDM组与非PTDM组在年龄、肾功能异常率 (5 7.1%及 30 .5 % )及阳性糖尿病家族史方面有显著性差异 ,但与环孢霉素谷A浓度值及急性排异发生率无关。PTDM组并发高渗性非酮性糖尿病昏迷 2例 ,各类感染 11例 ,感染率 5 2 4%。　结论　PTDM是一种与抗排异药物及移植肾功能密切相关的继发性糖尿病 ,处理不当易致严重后果 ,需引起临床足够重视。Objective[WT5”BZ] To study the clinical rules of posttransplantation diabetes mellitus(PTDM). [WT5”HZ]Methods[WT5”BZ] 21 patients treated from Dec. 1992 to Sept. 1998 were analysed. [WT5”HZ]Results[WT5”BZ] The morbidity of PTDM was 16 3% of total patients in the corresponding period.Between the groups of PTDM and NON PTDM,there was statistical significance in age, kidney function and family diabetic history. It was not related to CSA bottom concentration and acute rejection. In this group 2 cases were complicated by hyperosmolar nonketotic diabetic comas (9 5%) and 11 various infections (52 4%). [WT5”HZ]Conclusions[WT5”BZ] PTDM as a secondary diabetes due to antirejection drugs and allograft kidney function may cause serious consequences if it is treated improperly. [WT5”HZ]

关 键 词：肾移植 糖尿病 并发症 PTDM 

分 类 号：R699.2[医药卫生—泌尿科学]