ATP敏感钾通道在心血管系统中的作用  

The role of ATP-sensitive K^+ channels in the cardiovascular system

作　　者：孟繁学[1] 焦晓慧 韩大英[1] 

机构地区：[1]首都医科大学心血管生理研究室 [2]首都医科大学临床检测中心,北京100054

出　　处：《中国病理生理杂志》2000年第1期94-96,共3页Chinese Journal of Pathophysiology

摘　　要：years ago, Noma first applicated the patch\|clamp technique to CN\|treated mamammalian heart cells,evealed specific K + channels which were depressed by intracellular ATP at level greater than 1 mM.He suggested the ATP-sensitive channels are important for regulating cellular energy metabolism in the control of membrane exitability.Recent studies supported the hypothesis and suggested that ATP-sensitive channels play an important role in hypoxia,myocardial ischemia/reperfusion and is chemic preconditioning.years ago, Noma first applicated the patch\|clamp technique to CN\|treated mamammalian heart cells,evealed specific K + channels which were depressed by intracellular ATP at level greater than 1 mM.He suggested the ATP-sensitive channels are important for regulating cellular energy metabolism in the control of membrane exitability.Recent studies supported the hypothesis and suggested that ATP-sensitive channels play an important role in hypoxia,myocardial ischemia/reperfusion and is chemic preconditioning.

关 键 词：K通道 心血管系统 ATP 

分 类 号：R541.02[医药卫生—心血管疾病]