疱疹性咽峡炎患儿肌酸激酶同工酶和肌钙蛋白测定的临床意义  

THE CLINIC SIGNIFINANCE OF CREATINE KINASE ISOENZYME AND CARDIAC TROPONIN I IN CHILDREN WITH HERPANGINA

作　　者：王凤英[1] 孙勇[1] 

机构地区：[1]山东省泰安市中心医院儿科,271000

出　　处：《中国煤炭工业医学杂志》2012年第4期532-533,共2页Chinese Journal of Coal Industry Medicine

摘　　要：目的观察疱疹性咽峡炎患儿肌酸激酶同工酶(CK-MB)和肌钙蛋白(c-TnI)的表达情况,探讨其临床意义。方法采用全自动生化分析仪和全自动化学发光免疫分析仪,对疱疹性咽峡炎50例(疱疹组)和一般上呼吸道感染68例(普通组)患儿CK-MB和c-TnI进行检测。结果疱疹组和普通组CK-MB的平均值分别为(37.36±25.69)U/L和(23.88±12.34)U/L;二组c-TnI阳性率分别为79%和19%;二组患儿CK-MB和c-TnI比较差异有统计学意义。结论疱疹性咽峡炎较一般上呼吸道感染更易引起心肌损伤,对疱疹性咽峡炎患儿,要提高警惕,注意保护心肌。Objective To observe the performance of creatine kinase isoenzyme（cK- MB） and cardiac troponin l（cTnI） in children with herpangina,and to explore the clinical signifinance. Methods CK- MB and cTnI were tested 50 children with herpangina（herpangina group） and 68 children with common upper respiratory infection（common group） with automated chemiluminescence immunoassay analyzers and auto- matic biochemical analyzer. Results The mean value of CK- MB in herpangina group and common group were（37.36 ± 25.69）U/L and（23.88 ± 12.34）U/L; the positive rate of cTnI in two groups were 79 % and 19%. The differerances of CK - MB and cTnl were significant in two groups. Conclusion Herpangina causes myocardial damage more easely than common upper respiratory infection. We should elevate vigilance and ware to protect myoeardium for children with herpangina.

关 键 词：疱疹性咽峡炎 肌酸激酶同工酶 肌钙蛋白 

分 类 号：R766.12[医药卫生—耳鼻咽喉科]