ORK—CAM引导准分子激光非球面切削个体化术优化设计方案的临床验证  

The optimized project of ORK-CAM guided customized aspheric laser in situ keratomiteusis surgery

作　　者：匡丽晖[1] 金敏[1] 王小园[1] 高宗银[1] 杨为中[1] 黄雄飞[1] 朱远军[1] 张柳[1] 周传清[1] 任秋实[1] 

机构地区：[1]广州市第一人民医院眼科,广东510180

出　　处：《中国实用眼科杂志》2012年第4期391-393,共3页Chinese Journal of Practical Ophthalmology

基　　金：本论文为2010年广州市科技进步二等奖获奖项目的系列研究之一（GK10202）

摘　　要：目的评价ORK—CAM引导的准分子激光非球面切削个体化手术优化设计方案的有效性和安全性。方法选取2003年和2008年在广州市第一人民医院激光中心就诊的平均等效球镜度、角膜像差没有明显差异的近视患者300例分为两组，其中优化方案组150例（300只眼）接受ORK—CAM引导的非球面个性化切削手术，传统方案组150例（300只眼）接受传统LASIK手术。进行两组患者术前和术后6个月裸眼视力、残余等效球镜度、角膜像差和Q值的比较。结果术后6个月，2组患者裸眼视力差异无统计学意义（P〉0．05）。术后6个月，2组患者术后残余等效球镜度均减少，但两组间变化值比较差异无统计学意义（均P〉0．05）；两组患者角膜总体阶像差均方根值（RMS）、三阶像差均方根值（RMS3）、四阶像差均方根值（RMS4）、球差、慧差和Q值均增加，但优化方案组的增幅小于传统方案组，均P〈0．05。结论ORK—CAM引导的准分子激光非球面切削个体化手术优化设计方案能提高手术的有效性和安全性，能改善术后的视觉质量。Objective To estimate the validity and security of the optimized project of ORK-CAM guided customized aspheric laser in situ keratomiteuSis （LASIK） surgery. Methods Three hundred patients （600 eyes） registered to the Laser Center of The First Municipal People＇s Hospital of Guangzhou in 2003 and 2008, comparable in mean spherical equivalent and corneal aberration, were randomly assigned to two groups to receive the ORK-CAM guided aspheric customized excimer laser surgery （optimized project group, 150 patients, 300 eyes） or conventional LASIK surgery （conventional project group, 150 patients, 300 eyes）. Naked eye vision, spherical equivalent, corneal aberration and Q value were measured and compared between the two groups before and 6 months after the surgery. Results Six months after surgery, there were no statistical differences in naked eye vision （P 〉0.05）. Both two groups had lowered spherical equivalent but these parameters were not comparable between two groups in both absolute value and reduction from baseline （all P 〉 0.05）. While RMS, RMS3, RMS4, SphA, Coma and Q value increased in both groups. Optimized project group had less increase in these parameters than conventional project group. Conclusion Compared with the conventional spheric surgery, ORK-CAM guided aspheric customized excimer laser surgery can increase the validity and security and improve the visual quality.

关 键 词：角膜磨镶术 激光 屈光性角膜切削术 像差 非球面 治疗 

分 类 号：R657.51[医药卫生—外科学]