单纯外阴阴道假丝酵母菌病与细菌性阴道病现状调查及疗效分析  

Analysis Infection Condition and Curative Effect of Vulvovaginal Candi diasis and Bacterial Vaginosis

作　　者：李玉英[1] 

机构地区：[1]山东省泰安荣军医院,山东泰安271000

出　　处：《中华妇幼临床医学杂志（电子版）》2012年第2期180-182,共3页Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition)

摘　　要：目的探讨妇女外阴阴道假丝酵母菌病(VVC)及细菌性阴道病(BV)的感染状况及影响疗效的相关因素。方法随机选取2009年6月至2010年12月于本院妇科门诊就诊及查体的1280例非妊娠妇女的临床资料为研究对象,将确诊为VVC和BV的患者分别纳入VVC组(n=96)和BV组(n=124),并根据治疗配合情况,将上述两组继续分别分为A亚组(按医嘱用药者)和B亚组(未按要求用药或性伴侣拒绝接受治疗者)。采取问卷调查、病史采集、妇科查体及实验室检查等方式,对VVC和BV发病率、影响因素、治疗效果等进行对比分析(本研究遵循的程序符合本院人体试验委员会所制定的伦理学标准,得到该委员会批准)。结果本组VVC与BV发病率分别为7.5%和9.69%。VVC组患者乳酸杆菌检出率明显高于BV组患者,差异有统计学意义(P<0.01)。妇科炎症、避孕方式、个人卫生习惯及重复流产等对VVC和BV均有不同程度影响,而未规范治疗是影响其治疗效果的重要因素。经治疗后VVCA,B亚组与BV亚组1～2周及4～5周复诊结果均显示,痊愈率比较,差异均有统计学意义,而好转率及无效率因病例数较少,而未行统计学处理。结论 VVC和BV发病均与菌群失调有关,加强健康教育、进行规范治疗是预防和降低其复发率的有效措施。Objective To study the infection condition and curati ve effect of woman with vulvovaginal candidiasis（VVC） or bacterial vaginosis（BV）.Methods From June 2009 to December 2010,1280 non-pregnant outpa tients were enrolled in this study.Questionnaire investigation,medical history,gynecological checkup and lab results were collected.Incidence rate,influenc ing factors and curative effects were analyzed.The study protocol was approved by the Ethical Review Board of Investigation in Human Being of Taian Disabled Soldi er Hospital of Shandong.Informed consent was obtained from each patient.Results The incidence rate of VVC and BV were 7.5% and 9.69%,respectivel y.Vaginal lactobacillus had higher detection rate in VVC group than that in BV group（P0.01）.Gynecological inflammation,contraceptive methods,individual h abits,repeated abortion and so on,had the influence of different levels on VV C group and BV group.The key factor of affecting curative effect was not accept the standard treatment.There had significant difference between subgroup A and B in cure rate after treatment（P0.05）.Conclusions VVC and BV are associated with dysbacteriosis in vagina.To strengthen health education an d carry on the standard treatment are the effective action for reducing incide nce of VVC and BV.

关 键 词：外阴阴道假丝酵母菌病 细菌性阴道病 影响因素 治疗效果 健康教育 

分 类 号：R711.3[医药卫生—妇产科学]